Recombinant multi-species CIDEA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CIDEA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010]
The Alternative Names of target: CIDE-A,CIDEA,Cell death activator CIDE-A,Cell death-inducing DFFA-like effector A,Cidea,Lipid transferase CIDEA
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP4179-Ag-1/ GM-Tg-hg-IP4179-Ag-2 | Human CIDEA protein | Human |
| GM-Tg-rg-IP4179-Ag-1/ GM-Tg-rg-IP4179-Ag-2 | Rat CIDEA protein | Rat |
| GM-Tg-mg-IP4179-Ag-1/ GM-Tg-mg-IP4179-Ag-2 | Mouse CIDEA protein | Mouse |
| GM-Tg-cynog-IP4179-Ag-1/ GM-Tg-cynog-IP4179-Ag-2 | Cynomolgus/Rhesus macaque CIDEA protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP4179-Ag-1/ GM-Tg-felg-IP4179-Ag-2 | Feline CIDEA protein | Feline |
| GM-Tg-cang-IP4179-Ag-1/ GM-Tg-cang-IP4179-Ag-2 | Canine CIDEA protein | Canine |
| GM-Tg-bovg-IP4179-Ag-1/ GM-Tg-bovg-IP4179-Ag-2 | Bovine CIDEA protein | Bovine |
| GM-Tg-equg-IP4179-Ag-1/ GM-Tg-equg-IP4179-Ag-2 | Equine CIDEA protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP4179-Ag-1/ GM-Tg-hg-IP4179-Ag-2;
GM-Tg-rg-IP4179-Ag-1/ GM-Tg-rg-IP4179-Ag-2;
GM-Tg-mg-IP4179-Ag-1/ GM-Tg-mg-IP4179-Ag-2; GM-Tg-cynog-IP4179-Ag-1/ GM-Tg-cynog-IP4179-Ag-2; GM-Tg-felg-IP4179-Ag-1/ GM-Tg-felg-IP4179-Ag-2; GM-Tg-cang-IP4179-Ag-1/ GM-Tg-cang-IP4179-Ag-2; GM-Tg-bovg-IP4179-Ag-1/ GM-Tg-bovg-IP4179-Ag-2; GM-Tg-equg-IP4179-Ag-1/ GM-Tg-equg-IP4179-Ag-2 |
| Products Name | CIDEA protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CIDEA |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CIDEA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.