Recombinant multi-species U2AF2/U2AF65 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine U2AF2/U2AF65 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 65kDa,DEVDFB,Splicing factor U2AF 65 kDa subunit,U2 auxiliary factor 65 kDa subunit (hU2AF(65),U2 snRNP auxiliary factor large subunit,U2AF2,U2AF65,U2af2,hU2AF65)

Target products collectionGo to U2AF2/U2AF65 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP4130-Ag-1/ GM-Tg-hg-IP4130-Ag-2 Human U2AF2/U2AF65 protein Human
GM-Tg-rg-IP4130-Ag-1/ GM-Tg-rg-IP4130-Ag-2 Rat U2AF2/U2AF65 protein Rat
GM-Tg-mg-IP4130-Ag-1/ GM-Tg-mg-IP4130-Ag-2 Mouse U2AF2/U2AF65 protein Mouse
GM-Tg-cynog-IP4130-Ag-1/ GM-Tg-cynog-IP4130-Ag-2 Cynomolgus/Rhesus macaque U2AF2/U2AF65 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP4130-Ag-1/ GM-Tg-felg-IP4130-Ag-2 Feline U2AF2/U2AF65 protein Feline
GM-Tg-cang-IP4130-Ag-1/ GM-Tg-cang-IP4130-Ag-2 Canine U2AF2/U2AF65 protein Canine
GM-Tg-bovg-IP4130-Ag-1/ GM-Tg-bovg-IP4130-Ag-2 Bovine U2AF2/U2AF65 protein Bovine
GM-Tg-equg-IP4130-Ag-1/ GM-Tg-equg-IP4130-Ag-2 Equine U2AF2/U2AF65 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP4130-Ag-1/ GM-Tg-hg-IP4130-Ag-2; GM-Tg-rg-IP4130-Ag-1/ GM-Tg-rg-IP4130-Ag-2;
GM-Tg-mg-IP4130-Ag-1/ GM-Tg-mg-IP4130-Ag-2; GM-Tg-cynog-IP4130-Ag-1/ GM-Tg-cynog-IP4130-Ag-2;
GM-Tg-felg-IP4130-Ag-1/ GM-Tg-felg-IP4130-Ag-2; GM-Tg-cang-IP4130-Ag-1/ GM-Tg-cang-IP4130-Ag-2;
GM-Tg-bovg-IP4130-Ag-1/ GM-Tg-bovg-IP4130-Ag-2; GM-Tg-equg-IP4130-Ag-1/ GM-Tg-equg-IP4130-Ag-2
Products Name U2AF2/U2AF65 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name U2AF2/U2AF65
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine U2AF2/U2AF65 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.