Recombinant multi-species CHD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2810013C04Rik,2810040A01Rik,5630401D06Rik,ATP-dependent helicase CHD2,CHD-2,CHD2,Chd2,Chromodomain-helicase-DNA-binding protein 2,DEE94,EEOC
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP3928-Ag-1/ GM-Tg-hg-IP3928-Ag-2 | Human CHD2 protein | Human |
| GM-Tg-rg-IP3928-Ag-1/ GM-Tg-rg-IP3928-Ag-2 | Rat CHD2 protein | Rat |
| GM-Tg-mg-IP3928-Ag-1/ GM-Tg-mg-IP3928-Ag-2 | Mouse CHD2 protein | Mouse |
| GM-Tg-cynog-IP3928-Ag-1/ GM-Tg-cynog-IP3928-Ag-2 | Cynomolgus/Rhesus macaque CHD2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP3928-Ag-1/ GM-Tg-felg-IP3928-Ag-2 | Feline CHD2 protein | Feline |
| GM-Tg-cang-IP3928-Ag-1/ GM-Tg-cang-IP3928-Ag-2 | Canine CHD2 protein | Canine |
| GM-Tg-bovg-IP3928-Ag-1/ GM-Tg-bovg-IP3928-Ag-2 | Bovine CHD2 protein | Bovine |
| GM-Tg-equg-IP3928-Ag-1/ GM-Tg-equg-IP3928-Ag-2 | Equine CHD2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP3928-Ag-1/ GM-Tg-hg-IP3928-Ag-2;
GM-Tg-rg-IP3928-Ag-1/ GM-Tg-rg-IP3928-Ag-2;
GM-Tg-mg-IP3928-Ag-1/ GM-Tg-mg-IP3928-Ag-2; GM-Tg-cynog-IP3928-Ag-1/ GM-Tg-cynog-IP3928-Ag-2; GM-Tg-felg-IP3928-Ag-1/ GM-Tg-felg-IP3928-Ag-2; GM-Tg-cang-IP3928-Ag-1/ GM-Tg-cang-IP3928-Ag-2; GM-Tg-bovg-IP3928-Ag-1/ GM-Tg-bovg-IP3928-Ag-2; GM-Tg-equg-IP3928-Ag-1/ GM-Tg-equg-IP3928-Ag-2 |
| Products Name | CHD2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CHD2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.