Recombinant multi-species GRAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GRAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012]
The Alternative Names of target: DFNB114,GRAP,GRB2-related adapter protein

Target products collectionGo to GRAP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3734-Ag-1/ GM-Tg-hg-IP3734-Ag-2 Human GRAP protein Human
GM-Tg-rg-IP3734-Ag-1/ GM-Tg-rg-IP3734-Ag-2 Rat GRAP protein Rat
GM-Tg-mg-IP3734-Ag-1/ GM-Tg-mg-IP3734-Ag-2 Mouse GRAP protein Mouse
GM-Tg-cynog-IP3734-Ag-1/ GM-Tg-cynog-IP3734-Ag-2 Cynomolgus/Rhesus macaque GRAP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3734-Ag-1/ GM-Tg-felg-IP3734-Ag-2 Feline GRAP protein Feline
GM-Tg-cang-IP3734-Ag-1/ GM-Tg-cang-IP3734-Ag-2 Canine GRAP protein Canine
GM-Tg-bovg-IP3734-Ag-1/ GM-Tg-bovg-IP3734-Ag-2 Bovine GRAP protein Bovine
GM-Tg-equg-IP3734-Ag-1/ GM-Tg-equg-IP3734-Ag-2 Equine GRAP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3734-Ag-1/ GM-Tg-hg-IP3734-Ag-2; GM-Tg-rg-IP3734-Ag-1/ GM-Tg-rg-IP3734-Ag-2;
GM-Tg-mg-IP3734-Ag-1/ GM-Tg-mg-IP3734-Ag-2; GM-Tg-cynog-IP3734-Ag-1/ GM-Tg-cynog-IP3734-Ag-2;
GM-Tg-felg-IP3734-Ag-1/ GM-Tg-felg-IP3734-Ag-2; GM-Tg-cang-IP3734-Ag-1/ GM-Tg-cang-IP3734-Ag-2;
GM-Tg-bovg-IP3734-Ag-1/ GM-Tg-bovg-IP3734-Ag-2; GM-Tg-equg-IP3734-Ag-1/ GM-Tg-equg-IP3734-Ag-2
Products Name GRAP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GRAP
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GRAP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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