Recombinant multi-species NFAT5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NFAT5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: B130038B15Rik,CAG-8,CAG80,NF-AT5,NFAT5,NFATL1,NFATZ,Nfat,Nfat5,Nuclear factor of activated T-cells 5,OREBP,T-cell transcription factor NFAT5,TONEBP,TonEBP,TonEBP),Tonicity-responsive enhancer-binding protein (TonE-binding protein,mKIAA0827,nfatz
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP3722-Ag-1/ GM-Tg-hg-IP3722-Ag-2 | Human NFAT5 protein | Human |
| GM-Tg-rg-IP3722-Ag-1/ GM-Tg-rg-IP3722-Ag-2 | Rat NFAT5 protein | Rat |
| GM-Tg-mg-IP3722-Ag-1/ GM-Tg-mg-IP3722-Ag-2 | Mouse NFAT5 protein | Mouse |
| GM-Tg-cynog-IP3722-Ag-1/ GM-Tg-cynog-IP3722-Ag-2 | Cynomolgus/Rhesus macaque NFAT5 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP3722-Ag-1/ GM-Tg-felg-IP3722-Ag-2 | Feline NFAT5 protein | Feline |
| GM-Tg-cang-IP3722-Ag-1/ GM-Tg-cang-IP3722-Ag-2 | Canine NFAT5 protein | Canine |
| GM-Tg-bovg-IP3722-Ag-1/ GM-Tg-bovg-IP3722-Ag-2 | Bovine NFAT5 protein | Bovine |
| GM-Tg-equg-IP3722-Ag-1/ GM-Tg-equg-IP3722-Ag-2 | Equine NFAT5 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP3722-Ag-1/ GM-Tg-hg-IP3722-Ag-2;
GM-Tg-rg-IP3722-Ag-1/ GM-Tg-rg-IP3722-Ag-2;
GM-Tg-mg-IP3722-Ag-1/ GM-Tg-mg-IP3722-Ag-2; GM-Tg-cynog-IP3722-Ag-1/ GM-Tg-cynog-IP3722-Ag-2; GM-Tg-felg-IP3722-Ag-1/ GM-Tg-felg-IP3722-Ag-2; GM-Tg-cang-IP3722-Ag-1/ GM-Tg-cang-IP3722-Ag-2; GM-Tg-bovg-IP3722-Ag-1/ GM-Tg-bovg-IP3722-Ag-2; GM-Tg-equg-IP3722-Ag-1/ GM-Tg-equg-IP3722-Ag-2 |
| Products Name | NFAT5 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | NFAT5 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NFAT5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.