Recombinant multi-species POLD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]
The Alternative Names of target: 2410142G14Rik,DNA polymerase delta subunit 3,DNA polymerase delta subunit C,DNA polymerase delta subunit p66,DNA polymerase delta subunit p68,IMD122,P66,P68,POLD3,PPP1R128,Pold3

Target products collectionGo to POLD3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3716-Ag-1/ GM-Tg-hg-IP3716-Ag-2 Human POLD3 protein Human
GM-Tg-rg-IP3716-Ag-1/ GM-Tg-rg-IP3716-Ag-2 Rat POLD3 protein Rat
GM-Tg-mg-IP3716-Ag-1/ GM-Tg-mg-IP3716-Ag-2 Mouse POLD3 protein Mouse
GM-Tg-cynog-IP3716-Ag-1/ GM-Tg-cynog-IP3716-Ag-2 Cynomolgus/Rhesus macaque POLD3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3716-Ag-1/ GM-Tg-felg-IP3716-Ag-2 Feline POLD3 protein Feline
GM-Tg-cang-IP3716-Ag-1/ GM-Tg-cang-IP3716-Ag-2 Canine POLD3 protein Canine
GM-Tg-bovg-IP3716-Ag-1/ GM-Tg-bovg-IP3716-Ag-2 Bovine POLD3 protein Bovine
GM-Tg-equg-IP3716-Ag-1/ GM-Tg-equg-IP3716-Ag-2 Equine POLD3 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3716-Ag-1/ GM-Tg-hg-IP3716-Ag-2; GM-Tg-rg-IP3716-Ag-1/ GM-Tg-rg-IP3716-Ag-2;
GM-Tg-mg-IP3716-Ag-1/ GM-Tg-mg-IP3716-Ag-2; GM-Tg-cynog-IP3716-Ag-1/ GM-Tg-cynog-IP3716-Ag-2;
GM-Tg-felg-IP3716-Ag-1/ GM-Tg-felg-IP3716-Ag-2; GM-Tg-cang-IP3716-Ag-1/ GM-Tg-cang-IP3716-Ag-2;
GM-Tg-bovg-IP3716-Ag-1/ GM-Tg-bovg-IP3716-Ag-2; GM-Tg-equg-IP3716-Ag-1/ GM-Tg-equg-IP3716-Ag-2
Products Name POLD3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name POLD3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLD3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.