Recombinant multi-species IGF2BP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGF2BP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]
The Alternative Names of target: C330012H03Rik,Hepatocellular carcinoma autoantigen p62,IGF-II mRNA-binding protein 2,IGF2 mRNA-binding protein 2,IGF2BP2,IMP-2,IMP2,Igf2bp2,Imp2,Insulin-like growth factor 2 mRNA-binding protein 2,Neilsen,RGD1305614,VICKZ family member 2,VICKZ2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP3690-Ag-1/ GM-Tg-hg-IP3690-Ag-2 | Human IGF2BP2 protein | Human |
| GM-Tg-rg-IP3690-Ag-1/ GM-Tg-rg-IP3690-Ag-2 | Rat IGF2BP2 protein | Rat |
| GM-Tg-mg-IP3690-Ag-1/ GM-Tg-mg-IP3690-Ag-2 | Mouse IGF2BP2 protein | Mouse |
| GM-Tg-cynog-IP3690-Ag-1/ GM-Tg-cynog-IP3690-Ag-2 | Cynomolgus/Rhesus macaque IGF2BP2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP3690-Ag-1/ GM-Tg-felg-IP3690-Ag-2 | Feline IGF2BP2 protein | Feline |
| GM-Tg-cang-IP3690-Ag-1/ GM-Tg-cang-IP3690-Ag-2 | Canine IGF2BP2 protein | Canine |
| GM-Tg-bovg-IP3690-Ag-1/ GM-Tg-bovg-IP3690-Ag-2 | Bovine IGF2BP2 protein | Bovine |
| GM-Tg-equg-IP3690-Ag-1/ GM-Tg-equg-IP3690-Ag-2 | Equine IGF2BP2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP3690-Ag-1/ GM-Tg-hg-IP3690-Ag-2;
GM-Tg-rg-IP3690-Ag-1/ GM-Tg-rg-IP3690-Ag-2;
GM-Tg-mg-IP3690-Ag-1/ GM-Tg-mg-IP3690-Ag-2; GM-Tg-cynog-IP3690-Ag-1/ GM-Tg-cynog-IP3690-Ag-2; GM-Tg-felg-IP3690-Ag-1/ GM-Tg-felg-IP3690-Ag-2; GM-Tg-cang-IP3690-Ag-1/ GM-Tg-cang-IP3690-Ag-2; GM-Tg-bovg-IP3690-Ag-1/ GM-Tg-bovg-IP3690-Ag-2; GM-Tg-equg-IP3690-Ag-1/ GM-Tg-equg-IP3690-Ag-2 |
| Products Name | IGF2BP2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | IGF2BP2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGF2BP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.