Recombinant multi-species IGF2BP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGF2BP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2610101N11Rik,Ab2-255,CT98,IGF-II mRNA-binding protein 3,IGF2 mRNA-binding protein 3,IGF2BP3,IMP-3,IMP3,Igf2bp3,Insulin-like growth factor 2 mRNA-binding protein 3,KH domain-containing protein overexpressed in cancer (hKOC),KOC,KOC1,Koc13,Neilsen,RGD1306512,VICKZ family member 3,VICKZ3,mimp3

Target products collectionGo to IGF2BP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3689-Ag-1/ GM-Tg-hg-IP3689-Ag-2 Human IGF2BP3 protein Human
GM-Tg-rg-IP3689-Ag-1/ GM-Tg-rg-IP3689-Ag-2 Rat IGF2BP3 protein Rat
GM-Tg-mg-IP3689-Ag-1/ GM-Tg-mg-IP3689-Ag-2 Mouse IGF2BP3 protein Mouse
GM-Tg-cynog-IP3689-Ag-1/ GM-Tg-cynog-IP3689-Ag-2 Cynomolgus/Rhesus macaque IGF2BP3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3689-Ag-1/ GM-Tg-felg-IP3689-Ag-2 Feline IGF2BP3 protein Feline
GM-Tg-cang-IP3689-Ag-1/ GM-Tg-cang-IP3689-Ag-2 Canine IGF2BP3 protein Canine
GM-Tg-bovg-IP3689-Ag-1/ GM-Tg-bovg-IP3689-Ag-2 Bovine IGF2BP3 protein Bovine
GM-Tg-equg-IP3689-Ag-1/ GM-Tg-equg-IP3689-Ag-2 Equine IGF2BP3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3689-Ag-1/ GM-Tg-hg-IP3689-Ag-2; GM-Tg-rg-IP3689-Ag-1/ GM-Tg-rg-IP3689-Ag-2;
GM-Tg-mg-IP3689-Ag-1/ GM-Tg-mg-IP3689-Ag-2; GM-Tg-cynog-IP3689-Ag-1/ GM-Tg-cynog-IP3689-Ag-2;
GM-Tg-felg-IP3689-Ag-1/ GM-Tg-felg-IP3689-Ag-2; GM-Tg-cang-IP3689-Ag-1/ GM-Tg-cang-IP3689-Ag-2;
GM-Tg-bovg-IP3689-Ag-1/ GM-Tg-bovg-IP3689-Ag-2; GM-Tg-equg-IP3689-Ag-1/ GM-Tg-equg-IP3689-Ag-2
Products Name IGF2BP3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IGF2BP3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGF2BP3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.