Recombinant multi-species PRPF8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRPF8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 220 kDa U5 snRNP-specific protein,D11Bwg0410e,DBF3/PRP8,HPRP8,PRP8,PRP8 homolog,PRPC8,PRPF8,Pre-mRNA-processing-splicing factor 8,Prp8,Prpf8,RP13,SNRNP220,Sfprp8l,Splicing factor Prp8,p220

Target products collectionGo to PRPF8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3664-Ag-1/ GM-Tg-hg-IP3664-Ag-2 Human PRPF8 protein Human
GM-Tg-rg-IP3664-Ag-1/ GM-Tg-rg-IP3664-Ag-2 Rat PRPF8 protein Rat
GM-Tg-mg-IP3664-Ag-1/ GM-Tg-mg-IP3664-Ag-2 Mouse PRPF8 protein Mouse
GM-Tg-cynog-IP3664-Ag-1/ GM-Tg-cynog-IP3664-Ag-2 Cynomolgus/Rhesus macaque PRPF8 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3664-Ag-1/ GM-Tg-felg-IP3664-Ag-2 Feline PRPF8 protein Feline
GM-Tg-cang-IP3664-Ag-1/ GM-Tg-cang-IP3664-Ag-2 Canine PRPF8 protein Canine
GM-Tg-bovg-IP3664-Ag-1/ GM-Tg-bovg-IP3664-Ag-2 Bovine PRPF8 protein Bovine
GM-Tg-equg-IP3664-Ag-1/ GM-Tg-equg-IP3664-Ag-2 Equine PRPF8 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3664-Ag-1/ GM-Tg-hg-IP3664-Ag-2; GM-Tg-rg-IP3664-Ag-1/ GM-Tg-rg-IP3664-Ag-2;
GM-Tg-mg-IP3664-Ag-1/ GM-Tg-mg-IP3664-Ag-2; GM-Tg-cynog-IP3664-Ag-1/ GM-Tg-cynog-IP3664-Ag-2;
GM-Tg-felg-IP3664-Ag-1/ GM-Tg-felg-IP3664-Ag-2; GM-Tg-cang-IP3664-Ag-1/ GM-Tg-cang-IP3664-Ag-2;
GM-Tg-bovg-IP3664-Ag-1/ GM-Tg-bovg-IP3664-Ag-2; GM-Tg-equg-IP3664-Ag-1/ GM-Tg-equg-IP3664-Ag-2
Products Name PRPF8 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PRPF8
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRPF8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.