Recombinant multi-species PRPF8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRPF8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 220 kDa U5 snRNP-specific protein,D11Bwg0410e,DBF3/PRP8,HPRP8,PRP8,PRP8 homolog,PRPC8,PRPF8,Pre-mRNA-processing-splicing factor 8,Prp8,Prpf8,RP13,SNRNP220,Sfprp8l,Splicing factor Prp8,p220
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP3664-Ag-1/ GM-Tg-hg-IP3664-Ag-2 | Human PRPF8 protein | Human |
| GM-Tg-rg-IP3664-Ag-1/ GM-Tg-rg-IP3664-Ag-2 | Rat PRPF8 protein | Rat |
| GM-Tg-mg-IP3664-Ag-1/ GM-Tg-mg-IP3664-Ag-2 | Mouse PRPF8 protein | Mouse |
| GM-Tg-cynog-IP3664-Ag-1/ GM-Tg-cynog-IP3664-Ag-2 | Cynomolgus/Rhesus macaque PRPF8 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP3664-Ag-1/ GM-Tg-felg-IP3664-Ag-2 | Feline PRPF8 protein | Feline |
| GM-Tg-cang-IP3664-Ag-1/ GM-Tg-cang-IP3664-Ag-2 | Canine PRPF8 protein | Canine |
| GM-Tg-bovg-IP3664-Ag-1/ GM-Tg-bovg-IP3664-Ag-2 | Bovine PRPF8 protein | Bovine |
| GM-Tg-equg-IP3664-Ag-1/ GM-Tg-equg-IP3664-Ag-2 | Equine PRPF8 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP3664-Ag-1/ GM-Tg-hg-IP3664-Ag-2;
GM-Tg-rg-IP3664-Ag-1/ GM-Tg-rg-IP3664-Ag-2;
GM-Tg-mg-IP3664-Ag-1/ GM-Tg-mg-IP3664-Ag-2; GM-Tg-cynog-IP3664-Ag-1/ GM-Tg-cynog-IP3664-Ag-2; GM-Tg-felg-IP3664-Ag-1/ GM-Tg-felg-IP3664-Ag-2; GM-Tg-cang-IP3664-Ag-1/ GM-Tg-cang-IP3664-Ag-2; GM-Tg-bovg-IP3664-Ag-1/ GM-Tg-bovg-IP3664-Ag-2; GM-Tg-equg-IP3664-Ag-1/ GM-Tg-equg-IP3664-Ag-2 |
| Products Name | PRPF8 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PRPF8 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRPF8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.