Recombinant multi-species CEBP Alpha/CEBPA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CEBP Alpha/CEBPA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]
The Alternative Names of target: C/EBP alpha,C/EBP-alpha,C/ebpalpha,CBF-A,CCAAT/enhancer-binding protein alpha,CEBP,CEBP Alpha,CEBPA,Cebp,Cebpa,DBPCEP
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP3551-Ag-1/ GM-Tg-hg-IP3551-Ag-2 | Human CEBP Alpha/CEBPA protein | Human |
| GM-Tg-rg-IP3551-Ag-1/ GM-Tg-rg-IP3551-Ag-2 | Rat CEBP Alpha/CEBPA protein | Rat |
| GM-Tg-mg-IP3551-Ag-1/ GM-Tg-mg-IP3551-Ag-2 | Mouse CEBP Alpha/CEBPA protein | Mouse |
| GM-Tg-cynog-IP3551-Ag-1/ GM-Tg-cynog-IP3551-Ag-2 | Cynomolgus/Rhesus macaque CEBP Alpha/CEBPA protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP3551-Ag-1/ GM-Tg-felg-IP3551-Ag-2 | Feline CEBP Alpha/CEBPA protein | Feline |
| GM-Tg-cang-IP3551-Ag-1/ GM-Tg-cang-IP3551-Ag-2 | Canine CEBP Alpha/CEBPA protein | Canine |
| GM-Tg-bovg-IP3551-Ag-1/ GM-Tg-bovg-IP3551-Ag-2 | Bovine CEBP Alpha/CEBPA protein | Bovine |
| GM-Tg-equg-IP3551-Ag-1/ GM-Tg-equg-IP3551-Ag-2 | Equine CEBP Alpha/CEBPA protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP3551-Ag-1/ GM-Tg-hg-IP3551-Ag-2;
GM-Tg-rg-IP3551-Ag-1/ GM-Tg-rg-IP3551-Ag-2;
GM-Tg-mg-IP3551-Ag-1/ GM-Tg-mg-IP3551-Ag-2; GM-Tg-cynog-IP3551-Ag-1/ GM-Tg-cynog-IP3551-Ag-2; GM-Tg-felg-IP3551-Ag-1/ GM-Tg-felg-IP3551-Ag-2; GM-Tg-cang-IP3551-Ag-1/ GM-Tg-cang-IP3551-Ag-2; GM-Tg-bovg-IP3551-Ag-1/ GM-Tg-bovg-IP3551-Ag-2; GM-Tg-equg-IP3551-Ag-1/ GM-Tg-equg-IP3551-Ag-2 |
| Products Name | CEBP Alpha/CEBPA protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CEBP Alpha/CEBPA |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CEBP Alpha/CEBPA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.