Recombinant multi-species NXF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NXF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
The Alternative Names of target: MEX67,Mex67,Mex67h,Mvb1,NXF1,Nuclear RNA export factor 1,Nxf1,TAP,Tap,Tip-associated protein,Tip-associating protein,mRNA export factor TAP

Target products collectionGo to NXF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3540-Ag-1/ GM-Tg-hg-IP3540-Ag-2 Human NXF1 protein Human
GM-Tg-rg-IP3540-Ag-1/ GM-Tg-rg-IP3540-Ag-2 Rat NXF1 protein Rat
GM-Tg-mg-IP3540-Ag-1/ GM-Tg-mg-IP3540-Ag-2 Mouse NXF1 protein Mouse
GM-Tg-cynog-IP3540-Ag-1/ GM-Tg-cynog-IP3540-Ag-2 Cynomolgus/Rhesus macaque NXF1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3540-Ag-1/ GM-Tg-felg-IP3540-Ag-2 Feline NXF1 protein Feline
GM-Tg-cang-IP3540-Ag-1/ GM-Tg-cang-IP3540-Ag-2 Canine NXF1 protein Canine
GM-Tg-bovg-IP3540-Ag-1/ GM-Tg-bovg-IP3540-Ag-2 Bovine NXF1 protein Bovine
GM-Tg-equg-IP3540-Ag-1/ GM-Tg-equg-IP3540-Ag-2 Equine NXF1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3540-Ag-1/ GM-Tg-hg-IP3540-Ag-2; GM-Tg-rg-IP3540-Ag-1/ GM-Tg-rg-IP3540-Ag-2;
GM-Tg-mg-IP3540-Ag-1/ GM-Tg-mg-IP3540-Ag-2; GM-Tg-cynog-IP3540-Ag-1/ GM-Tg-cynog-IP3540-Ag-2;
GM-Tg-felg-IP3540-Ag-1/ GM-Tg-felg-IP3540-Ag-2; GM-Tg-cang-IP3540-Ag-1/ GM-Tg-cang-IP3540-Ag-2;
GM-Tg-bovg-IP3540-Ag-1/ GM-Tg-bovg-IP3540-Ag-2; GM-Tg-equg-IP3540-Ag-1/ GM-Tg-equg-IP3540-Ag-2
Products Name NXF1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NXF1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NXF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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