Recombinant multi-species MARCHF6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MARCHF6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of a family of membrane-associated E3 ubiquitin ligases containing RING-CH-type zinc finger motifs. Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormone signalling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
The Alternative Names of target: 3830408G03,45722,DOA10,Doa10 homolog,E3 ubiquitin-protein ligase MARCHF6,F830029L24Rik,FAME3,FCMTE3,MARCH-VI,MARCH6,MARCHF6,March6,Marchf6,Membrane-associated RING finger protein 6,Membrane-associated RING-CH protein VI (MARCH-VI),Protein TEB-4,RGD1310927,RGD1565757,RING finger protein 176,RING-type E3 ubiquitin transferase MARCHF6,RNF176,TEB4,mKIAA0597

Target products collectionGo to MARCHF6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3468-Ag-1/ GM-Tg-hg-IP3468-Ag-2 Human MARCHF6 protein Human
GM-Tg-rg-IP3468-Ag-1/ GM-Tg-rg-IP3468-Ag-2 Rat MARCHF6 protein Rat
GM-Tg-mg-IP3468-Ag-1/ GM-Tg-mg-IP3468-Ag-2 Mouse MARCHF6 protein Mouse
GM-Tg-cynog-IP3468-Ag-1/ GM-Tg-cynog-IP3468-Ag-2 Cynomolgus/Rhesus macaque MARCHF6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3468-Ag-1/ GM-Tg-felg-IP3468-Ag-2 Feline MARCHF6 protein Feline
GM-Tg-cang-IP3468-Ag-1/ GM-Tg-cang-IP3468-Ag-2 Canine MARCHF6 protein Canine
GM-Tg-bovg-IP3468-Ag-1/ GM-Tg-bovg-IP3468-Ag-2 Bovine MARCHF6 protein Bovine
GM-Tg-equg-IP3468-Ag-1/ GM-Tg-equg-IP3468-Ag-2 Equine MARCHF6 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3468-Ag-1/ GM-Tg-hg-IP3468-Ag-2; GM-Tg-rg-IP3468-Ag-1/ GM-Tg-rg-IP3468-Ag-2;
GM-Tg-mg-IP3468-Ag-1/ GM-Tg-mg-IP3468-Ag-2; GM-Tg-cynog-IP3468-Ag-1/ GM-Tg-cynog-IP3468-Ag-2;
GM-Tg-felg-IP3468-Ag-1/ GM-Tg-felg-IP3468-Ag-2; GM-Tg-cang-IP3468-Ag-1/ GM-Tg-cang-IP3468-Ag-2;
GM-Tg-bovg-IP3468-Ag-1/ GM-Tg-bovg-IP3468-Ag-2; GM-Tg-equg-IP3468-Ag-1/ GM-Tg-equg-IP3468-Ag-2
Products Name MARCHF6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MARCHF6
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MARCHF6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.