Recombinant multi-species BCKDK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCKDK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
The Alternative Names of target: BCKDH kinase,BCKDHKIN,BCKDK,BCKDKD,BDK,Bckdk,Branched-chain alpha-ketoacid dehydrogenase kinase,[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase,mitochondrial
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP3466-Ag-1/ GM-Tg-hg-IP3466-Ag-2 | Human BCKDK protein | Human |
| GM-Tg-rg-IP3466-Ag-1/ GM-Tg-rg-IP3466-Ag-2 | Rat BCKDK protein | Rat |
| GM-Tg-mg-IP3466-Ag-1/ GM-Tg-mg-IP3466-Ag-2 | Mouse BCKDK protein | Mouse |
| GM-Tg-cynog-IP3466-Ag-1/ GM-Tg-cynog-IP3466-Ag-2 | Cynomolgus/Rhesus macaque BCKDK protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP3466-Ag-1/ GM-Tg-felg-IP3466-Ag-2 | Feline BCKDK protein | Feline |
| GM-Tg-cang-IP3466-Ag-1/ GM-Tg-cang-IP3466-Ag-2 | Canine BCKDK protein | Canine |
| GM-Tg-bovg-IP3466-Ag-1/ GM-Tg-bovg-IP3466-Ag-2 | Bovine BCKDK protein | Bovine |
| GM-Tg-equg-IP3466-Ag-1/ GM-Tg-equg-IP3466-Ag-2 | Equine BCKDK protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP3466-Ag-1/ GM-Tg-hg-IP3466-Ag-2;
GM-Tg-rg-IP3466-Ag-1/ GM-Tg-rg-IP3466-Ag-2;
GM-Tg-mg-IP3466-Ag-1/ GM-Tg-mg-IP3466-Ag-2; GM-Tg-cynog-IP3466-Ag-1/ GM-Tg-cynog-IP3466-Ag-2; GM-Tg-felg-IP3466-Ag-1/ GM-Tg-felg-IP3466-Ag-2; GM-Tg-cang-IP3466-Ag-1/ GM-Tg-cang-IP3466-Ag-2; GM-Tg-bovg-IP3466-Ag-1/ GM-Tg-bovg-IP3466-Ag-2; GM-Tg-equg-IP3466-Ag-1/ GM-Tg-equg-IP3466-Ag-2 |
| Products Name | BCKDK protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | BCKDK |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCKDK protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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Through
expression in mammalian cell lines, GMab has
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myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.