Recombinant multi-species STUB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine STUB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2. [provided by RefSeq, Jun 2014]
The Alternative Names of target: 0610033N24Rik,2210017D18Rik,2310040B03Rik,Antigen NY-CO-7,CHIP,CLL-associated antigen KW-8,Carboxy terminus of Hsp70-interacting protein,Chip,E3 ubiquitin-protein ligase CHIP,HSPABP2,NY-CO-7,RING-type E3 ubiquitin transferase CHIP,SCA48,SCAR16,SDCCAG7,STIP1 homology and U box-containing protein 1,STUB1,Stub1,UBOX1

Target products collectionGo to STUB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3452-Ag-1/ GM-Tg-hg-IP3452-Ag-2 Human STUB1 protein Human
GM-Tg-rg-IP3452-Ag-1/ GM-Tg-rg-IP3452-Ag-2 Rat STUB1 protein Rat
GM-Tg-mg-IP3452-Ag-1/ GM-Tg-mg-IP3452-Ag-2 Mouse STUB1 protein Mouse
GM-Tg-cynog-IP3452-Ag-1/ GM-Tg-cynog-IP3452-Ag-2 Cynomolgus/Rhesus macaque STUB1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3452-Ag-1/ GM-Tg-felg-IP3452-Ag-2 Feline STUB1 protein Feline
GM-Tg-cang-IP3452-Ag-1/ GM-Tg-cang-IP3452-Ag-2 Canine STUB1 protein Canine
GM-Tg-bovg-IP3452-Ag-1/ GM-Tg-bovg-IP3452-Ag-2 Bovine STUB1 protein Bovine
GM-Tg-equg-IP3452-Ag-1/ GM-Tg-equg-IP3452-Ag-2 Equine STUB1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3452-Ag-1/ GM-Tg-hg-IP3452-Ag-2; GM-Tg-rg-IP3452-Ag-1/ GM-Tg-rg-IP3452-Ag-2;
GM-Tg-mg-IP3452-Ag-1/ GM-Tg-mg-IP3452-Ag-2; GM-Tg-cynog-IP3452-Ag-1/ GM-Tg-cynog-IP3452-Ag-2;
GM-Tg-felg-IP3452-Ag-1/ GM-Tg-felg-IP3452-Ag-2; GM-Tg-cang-IP3452-Ag-1/ GM-Tg-cang-IP3452-Ag-2;
GM-Tg-bovg-IP3452-Ag-1/ GM-Tg-bovg-IP3452-Ag-2; GM-Tg-equg-IP3452-Ag-1/ GM-Tg-equg-IP3452-Ag-2
Products Name STUB1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name STUB1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine STUB1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.