Recombinant multi-species DRP1/DNM1L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DRP1/DNM1L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
The Alternative Names of target: 6330417M19Rik,DLP1,DNM1L,DRP1,DVLP,DYMPLE,Dlp1,Dnm1l,Dnm1p/Vps1p-like protein (DVLP),Dnml1,Dnmlp1,Drp1,Dynamin family member proline-rich carboxyl-terminal domain less (Dymple),Dynamin-1-like protein,Dynamin-like protein,Dynamin-like protein 4,Dynamin-like protein IV (HdynIV),Dynamin-related protein 1,EMPF,EMPF1,HDYNIV,OPA5,python
Go
to DRP1/DNM1L products collection
>>
(antibodies,
antigen, VLP, mRNA, ORF viral vector, etc)
Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP3218-Ag-1/ GM-Tg-hg-IP3218-Ag-2 | Human DRP1/DNM1L protein | Human |
| GM-Tg-rg-IP3218-Ag-1/ GM-Tg-rg-IP3218-Ag-2 | Rat DRP1/DNM1L protein | Rat |
| GM-Tg-mg-IP3218-Ag-1/ GM-Tg-mg-IP3218-Ag-2 | Mouse DRP1/DNM1L protein | Mouse |
| GM-Tg-cynog-IP3218-Ag-1/ GM-Tg-cynog-IP3218-Ag-2 | Cynomolgus/Rhesus macaque DRP1/DNM1L protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP3218-Ag-1/ GM-Tg-felg-IP3218-Ag-2 | Feline DRP1/DNM1L protein | Feline |
| GM-Tg-cang-IP3218-Ag-1/ GM-Tg-cang-IP3218-Ag-2 | Canine DRP1/DNM1L protein | Canine |
| GM-Tg-bovg-IP3218-Ag-1/ GM-Tg-bovg-IP3218-Ag-2 | Bovine DRP1/DNM1L protein | Bovine |
| GM-Tg-equg-IP3218-Ag-1/ GM-Tg-equg-IP3218-Ag-2 | Equine DRP1/DNM1L protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP3218-Ag-1/ GM-Tg-hg-IP3218-Ag-2;
GM-Tg-rg-IP3218-Ag-1/ GM-Tg-rg-IP3218-Ag-2;
GM-Tg-mg-IP3218-Ag-1/ GM-Tg-mg-IP3218-Ag-2; GM-Tg-cynog-IP3218-Ag-1/ GM-Tg-cynog-IP3218-Ag-2; GM-Tg-felg-IP3218-Ag-1/ GM-Tg-felg-IP3218-Ag-2; GM-Tg-cang-IP3218-Ag-1/ GM-Tg-cang-IP3218-Ag-2; GM-Tg-bovg-IP3218-Ag-1/ GM-Tg-bovg-IP3218-Ag-2; GM-Tg-equg-IP3218-Ag-1/ GM-Tg-equg-IP3218-Ag-2 |
| Products Name | DRP1/DNM1L protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DRP1/DNM1L |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DRP1/DNM1L protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.