Recombinant multi-species TANK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TANK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
The Alternative Names of target: E430026L09Rik,I-TRAF,ITRAF,TANK,TRAF family member-associated NF-kappa-B activator,TRAF-interacting protein (I-TRAF),TRAF2,Tank

Target products collectionGo to TANK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2982-Ag-1/ GM-Tg-hg-IP2982-Ag-2 Human TANK protein Human
GM-Tg-rg-IP2982-Ag-1/ GM-Tg-rg-IP2982-Ag-2 Rat TANK protein Rat
GM-Tg-mg-IP2982-Ag-1/ GM-Tg-mg-IP2982-Ag-2 Mouse TANK protein Mouse
GM-Tg-cynog-IP2982-Ag-1/ GM-Tg-cynog-IP2982-Ag-2 Cynomolgus/Rhesus macaque TANK protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2982-Ag-1/ GM-Tg-felg-IP2982-Ag-2 Feline TANK protein Feline
GM-Tg-cang-IP2982-Ag-1/ GM-Tg-cang-IP2982-Ag-2 Canine TANK protein Canine
GM-Tg-bovg-IP2982-Ag-1/ GM-Tg-bovg-IP2982-Ag-2 Bovine TANK protein Bovine
GM-Tg-equg-IP2982-Ag-1/ GM-Tg-equg-IP2982-Ag-2 Equine TANK protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2982-Ag-1/ GM-Tg-hg-IP2982-Ag-2; GM-Tg-rg-IP2982-Ag-1/ GM-Tg-rg-IP2982-Ag-2;
GM-Tg-mg-IP2982-Ag-1/ GM-Tg-mg-IP2982-Ag-2; GM-Tg-cynog-IP2982-Ag-1/ GM-Tg-cynog-IP2982-Ag-2;
GM-Tg-felg-IP2982-Ag-1/ GM-Tg-felg-IP2982-Ag-2; GM-Tg-cang-IP2982-Ag-1/ GM-Tg-cang-IP2982-Ag-2;
GM-Tg-bovg-IP2982-Ag-1/ GM-Tg-bovg-IP2982-Ag-2; GM-Tg-equg-IP2982-Ag-1/ GM-Tg-equg-IP2982-Ag-2
Products Name TANK protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TANK
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TANK protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.