Recombinant multi-species NR2E3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NR2E3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: A930035N01Rik,ESCS,NR2E3,Nr2e3,Nuclear receptor subfamily 2 group E member 3,PNR,Photoreceptor-specific nuclear receptor,RNR,RP37,Retina-specific nuclear receptor,rd7

Target products collectionGo to NR2E3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2976-Ag-1/ GM-Tg-hg-IP2976-Ag-2 Human NR2E3 protein Human
GM-Tg-rg-IP2976-Ag-1/ GM-Tg-rg-IP2976-Ag-2 Rat NR2E3 protein Rat
GM-Tg-mg-IP2976-Ag-1/ GM-Tg-mg-IP2976-Ag-2 Mouse NR2E3 protein Mouse
GM-Tg-cynog-IP2976-Ag-1/ GM-Tg-cynog-IP2976-Ag-2 Cynomolgus/Rhesus macaque NR2E3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2976-Ag-1/ GM-Tg-felg-IP2976-Ag-2 Feline NR2E3 protein Feline
GM-Tg-cang-IP2976-Ag-1/ GM-Tg-cang-IP2976-Ag-2 Canine NR2E3 protein Canine
GM-Tg-bovg-IP2976-Ag-1/ GM-Tg-bovg-IP2976-Ag-2 Bovine NR2E3 protein Bovine
GM-Tg-equg-IP2976-Ag-1/ GM-Tg-equg-IP2976-Ag-2 Equine NR2E3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2976-Ag-1/ GM-Tg-hg-IP2976-Ag-2; GM-Tg-rg-IP2976-Ag-1/ GM-Tg-rg-IP2976-Ag-2;
GM-Tg-mg-IP2976-Ag-1/ GM-Tg-mg-IP2976-Ag-2; GM-Tg-cynog-IP2976-Ag-1/ GM-Tg-cynog-IP2976-Ag-2;
GM-Tg-felg-IP2976-Ag-1/ GM-Tg-felg-IP2976-Ag-2; GM-Tg-cang-IP2976-Ag-1/ GM-Tg-cang-IP2976-Ag-2;
GM-Tg-bovg-IP2976-Ag-1/ GM-Tg-bovg-IP2976-Ag-2; GM-Tg-equg-IP2976-Ag-1/ GM-Tg-equg-IP2976-Ag-2
Products Name NR2E3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NR2E3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NR2E3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.