Recombinant multi-species STIP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine STIP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]
The Alternative Names of target: HEL-S-94n,HOP,Hop,Hsc70/Hsp90-organizing protein (Hop),IEF-SSP-3521,P60,Renal carcinoma antigen NY-REN-11,STI1,STI1L,STIP1,Sti1,Stip1,Stress-induced-phosphoprotein 1,Transformation-sensitive protein IEF SSP 3521,p60

Target products collectionGo to STIP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2759-Ag-1/ GM-Tg-hg-IP2759-Ag-2 Human STIP1 protein Human
GM-Tg-rg-IP2759-Ag-1/ GM-Tg-rg-IP2759-Ag-2 Rat STIP1 protein Rat
GM-Tg-mg-IP2759-Ag-1/ GM-Tg-mg-IP2759-Ag-2 Mouse STIP1 protein Mouse
GM-Tg-cynog-IP2759-Ag-1/ GM-Tg-cynog-IP2759-Ag-2 Cynomolgus/Rhesus macaque STIP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2759-Ag-1/ GM-Tg-felg-IP2759-Ag-2 Feline STIP1 protein Feline
GM-Tg-cang-IP2759-Ag-1/ GM-Tg-cang-IP2759-Ag-2 Canine STIP1 protein Canine
GM-Tg-bovg-IP2759-Ag-1/ GM-Tg-bovg-IP2759-Ag-2 Bovine STIP1 protein Bovine
GM-Tg-equg-IP2759-Ag-1/ GM-Tg-equg-IP2759-Ag-2 Equine STIP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2759-Ag-1/ GM-Tg-hg-IP2759-Ag-2; GM-Tg-rg-IP2759-Ag-1/ GM-Tg-rg-IP2759-Ag-2;
GM-Tg-mg-IP2759-Ag-1/ GM-Tg-mg-IP2759-Ag-2; GM-Tg-cynog-IP2759-Ag-1/ GM-Tg-cynog-IP2759-Ag-2;
GM-Tg-felg-IP2759-Ag-1/ GM-Tg-felg-IP2759-Ag-2; GM-Tg-cang-IP2759-Ag-1/ GM-Tg-cang-IP2759-Ag-2;
GM-Tg-bovg-IP2759-Ag-1/ GM-Tg-bovg-IP2759-Ag-2; GM-Tg-equg-IP2759-Ag-1/ GM-Tg-equg-IP2759-Ag-2
Products Name STIP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name STIP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine STIP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.