Recombinant multi-species SHANK3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SHANK3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012]
The Alternative Names of target: DEL22q13.3,PROSAP2,PSAP2,Proline-rich synapse-associated protein 2 (ProSAP2),Prosap2,SCZD15,SH3 and multiple ankyrin repeat domains protein 3,SHANK3,SPANK-2,Shank3,Spank-2,proSAP2

Target products collectionGo to SHANK3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2737-Ag-1/ GM-Tg-hg-IP2737-Ag-2 Human SHANK3 protein Human
GM-Tg-rg-IP2737-Ag-1/ GM-Tg-rg-IP2737-Ag-2 Rat SHANK3 protein Rat
GM-Tg-mg-IP2737-Ag-1/ GM-Tg-mg-IP2737-Ag-2 Mouse SHANK3 protein Mouse
GM-Tg-cynog-IP2737-Ag-1/ GM-Tg-cynog-IP2737-Ag-2 Cynomolgus/Rhesus macaque SHANK3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2737-Ag-1/ GM-Tg-felg-IP2737-Ag-2 Feline SHANK3 protein Feline
GM-Tg-cang-IP2737-Ag-1/ GM-Tg-cang-IP2737-Ag-2 Canine SHANK3 protein Canine
GM-Tg-bovg-IP2737-Ag-1/ GM-Tg-bovg-IP2737-Ag-2 Bovine SHANK3 protein Bovine
GM-Tg-equg-IP2737-Ag-1/ GM-Tg-equg-IP2737-Ag-2 Equine SHANK3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2737-Ag-1/ GM-Tg-hg-IP2737-Ag-2; GM-Tg-rg-IP2737-Ag-1/ GM-Tg-rg-IP2737-Ag-2;
GM-Tg-mg-IP2737-Ag-1/ GM-Tg-mg-IP2737-Ag-2; GM-Tg-cynog-IP2737-Ag-1/ GM-Tg-cynog-IP2737-Ag-2;
GM-Tg-felg-IP2737-Ag-1/ GM-Tg-felg-IP2737-Ag-2; GM-Tg-cang-IP2737-Ag-1/ GM-Tg-cang-IP2737-Ag-2;
GM-Tg-bovg-IP2737-Ag-1/ GM-Tg-bovg-IP2737-Ag-2; GM-Tg-equg-IP2737-Ag-1/ GM-Tg-equg-IP2737-Ag-2
Products Name SHANK3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SHANK3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SHANK3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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