Recombinant multi-species RAD51C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RAD51C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
The Alternative Names of target: BROVCA3,DNA repair protein RAD51 homolog 3,FANCO,R51H3,RAD51 homolog C,RAD51-like protein 2,RAD51C,RAD51L2,RGD1563765,Rad51c,Rad51l2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2689-Ag-1/ GM-Tg-hg-IP2689-Ag-2 | Human RAD51C protein | Human |
| GM-Tg-rg-IP2689-Ag-1/ GM-Tg-rg-IP2689-Ag-2 | Rat RAD51C protein | Rat |
| GM-Tg-mg-IP2689-Ag-1/ GM-Tg-mg-IP2689-Ag-2 | Mouse RAD51C protein | Mouse |
| GM-Tg-cynog-IP2689-Ag-1/ GM-Tg-cynog-IP2689-Ag-2 | Cynomolgus/Rhesus macaque RAD51C protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2689-Ag-1/ GM-Tg-felg-IP2689-Ag-2 | Feline RAD51C protein | Feline |
| GM-Tg-cang-IP2689-Ag-1/ GM-Tg-cang-IP2689-Ag-2 | Canine RAD51C protein | Canine |
| GM-Tg-bovg-IP2689-Ag-1/ GM-Tg-bovg-IP2689-Ag-2 | Bovine RAD51C protein | Bovine |
| GM-Tg-equg-IP2689-Ag-1/ GM-Tg-equg-IP2689-Ag-2 | Equine RAD51C protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP2689-Ag-1/ GM-Tg-hg-IP2689-Ag-2;
GM-Tg-rg-IP2689-Ag-1/ GM-Tg-rg-IP2689-Ag-2;
GM-Tg-mg-IP2689-Ag-1/ GM-Tg-mg-IP2689-Ag-2; GM-Tg-cynog-IP2689-Ag-1/ GM-Tg-cynog-IP2689-Ag-2; GM-Tg-felg-IP2689-Ag-1/ GM-Tg-felg-IP2689-Ag-2; GM-Tg-cang-IP2689-Ag-1/ GM-Tg-cang-IP2689-Ag-2; GM-Tg-bovg-IP2689-Ag-1/ GM-Tg-bovg-IP2689-Ag-2; GM-Tg-equg-IP2689-Ag-1/ GM-Tg-equg-IP2689-Ag-2 |
| Products Name | RAD51C protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RAD51C |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RAD51C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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Through
expression in mammalian cell lines, GMab has
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.