Recombinant multi-species PTPN12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTPN12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
The Alternative Names of target: PTPN12,Tyrosine-protein phosphatase non-receptor type 12,PTP-PEST, Protein-tyrosine phosphatase G1 (PTPG1),PTPG1,PTP-PEST

Target products collectionGo to PTPN12 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2678-Ab-1/ GM-Tg-hg-IP2678-Ab-2 Human PTPN12 protein Human
GM-Tg-rg-IP2678-Ab-1/ GM-Tg-rg-IP2678-Ab-2 Rat PTPN12 protein Rat
GM-Tg-mg-IP2678-Ab-1/ GM-Tg-mg-IP2678-Ab-2 Mouse PTPN12 protein Mouse
GM-Tg-cynog-IP2678-Ab-1/ GM-Tg-cynog-IP2678-Ab-2 Cynomolgus/Rhesus macaque PTPN12 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2678-Ab-1/ GM-Tg-felg-IP2678-Ab-2 Feline PTPN12 protein Feline
GM-Tg-cang-IP2678-Ab-1/ GM-Tg-cang-IP2678-Ab-2 Canine PTPN12 protein Canine
GM-Tg-bovg-IP2678-Ab-1/ GM-Tg-bovg-IP2678-Ab-2 Bovine PTPN12 protein Bovine
GM-Tg-equg-IP2678-Ab-1/ GM-Tg-equg-IP2678-Ab-2 Equine PTPN12 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2678-Ab-1/ GM-Tg-hg-IP2678-Ab-2; GM-Tg-rg-IP2678-Ab-1/ GM-Tg-rg-IP2678-Ab-2;
GM-Tg-mg-IP2678-Ab-1/ GM-Tg-mg-IP2678-Ab-2; GM-Tg-cynog-IP2678-Ab-1/ GM-Tg-cynog-IP2678-Ab-2;
GM-Tg-felg-IP2678-Ab-1/ GM-Tg-felg-IP2678-Ab-2; GM-Tg-cang-IP2678-Ab-1/ GM-Tg-cang-IP2678-Ab-2;
GM-Tg-bovg-IP2678-Ab-1/ GM-Tg-bovg-IP2678-Ab-2; GM-Tg-equg-IP2678-Ab-1/ GM-Tg-equg-IP2678-Ab-2
Products Name PTPN12 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PTPN12
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTPN12 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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