Recombinant multi-species Aiolos/IKZF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Aiolos/IKZF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
The Alternative Names of target: 5830411O07Rik,AIO,AIOLOS,Aiolos,IKZF3,IMD84,Ikaros family zinc finger protein 3,Ikzf3,ZNFN1A3,Zfpn1a3,Zinc finger protein Aiolos,Znfn1a3

Target products collectionGo to Aiolos/IKZF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2547-Ag-1/ GM-Tg-hg-IP2547-Ag-2 Human Aiolos/IKZF3 protein Human
GM-Tg-rg-IP2547-Ag-1/ GM-Tg-rg-IP2547-Ag-2 Rat Aiolos/IKZF3 protein Rat
GM-Tg-mg-IP2547-Ag-1/ GM-Tg-mg-IP2547-Ag-2 Mouse Aiolos/IKZF3 protein Mouse
GM-Tg-cynog-IP2547-Ag-1/ GM-Tg-cynog-IP2547-Ag-2 Cynomolgus/Rhesus macaque Aiolos/IKZF3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2547-Ag-1/ GM-Tg-felg-IP2547-Ag-2 Feline Aiolos/IKZF3 protein Feline
GM-Tg-cang-IP2547-Ag-1/ GM-Tg-cang-IP2547-Ag-2 Canine Aiolos/IKZF3 protein Canine
GM-Tg-bovg-IP2547-Ag-1/ GM-Tg-bovg-IP2547-Ag-2 Bovine Aiolos/IKZF3 protein Bovine
GM-Tg-equg-IP2547-Ag-1/ GM-Tg-equg-IP2547-Ag-2 Equine Aiolos/IKZF3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2547-Ag-1/ GM-Tg-hg-IP2547-Ag-2; GM-Tg-rg-IP2547-Ag-1/ GM-Tg-rg-IP2547-Ag-2;
GM-Tg-mg-IP2547-Ag-1/ GM-Tg-mg-IP2547-Ag-2; GM-Tg-cynog-IP2547-Ag-1/ GM-Tg-cynog-IP2547-Ag-2;
GM-Tg-felg-IP2547-Ag-1/ GM-Tg-felg-IP2547-Ag-2; GM-Tg-cang-IP2547-Ag-1/ GM-Tg-cang-IP2547-Ag-2;
GM-Tg-bovg-IP2547-Ag-1/ GM-Tg-bovg-IP2547-Ag-2; GM-Tg-equg-IP2547-Ag-1/ GM-Tg-equg-IP2547-Ag-2
Products Name Aiolos/IKZF3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Aiolos/IKZF3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Aiolos/IKZF3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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