Recombinant multi-species FOXA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FOXA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
The Alternative Names of target: FOXA2,Forkhead box protein A2,Foxa2,HNF-3-beta,HNF-3B,HNF-3b,HNF3-beta,HNF3B,HNF3beta,Hepatocyte nuclear factor 3-beta,Hnf-3b,Hnf3b,TCF3B,Tcf-3b,Tcf3b,Transcription factor 3B (TCF-3B)

Target products collectionGo to FOXA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2505-Ag-1/ GM-Tg-hg-IP2505-Ag-2 Human FOXA2 protein Human
GM-Tg-rg-IP2505-Ag-1/ GM-Tg-rg-IP2505-Ag-2 Rat FOXA2 protein Rat
GM-Tg-mg-IP2505-Ag-1/ GM-Tg-mg-IP2505-Ag-2 Mouse FOXA2 protein Mouse
GM-Tg-cynog-IP2505-Ag-1/ GM-Tg-cynog-IP2505-Ag-2 Cynomolgus/Rhesus macaque FOXA2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2505-Ag-1/ GM-Tg-felg-IP2505-Ag-2 Feline FOXA2 protein Feline
GM-Tg-cang-IP2505-Ag-1/ GM-Tg-cang-IP2505-Ag-2 Canine FOXA2 protein Canine
GM-Tg-bovg-IP2505-Ag-1/ GM-Tg-bovg-IP2505-Ag-2 Bovine FOXA2 protein Bovine
GM-Tg-equg-IP2505-Ag-1/ GM-Tg-equg-IP2505-Ag-2 Equine FOXA2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2505-Ag-1/ GM-Tg-hg-IP2505-Ag-2; GM-Tg-rg-IP2505-Ag-1/ GM-Tg-rg-IP2505-Ag-2;
GM-Tg-mg-IP2505-Ag-1/ GM-Tg-mg-IP2505-Ag-2; GM-Tg-cynog-IP2505-Ag-1/ GM-Tg-cynog-IP2505-Ag-2;
GM-Tg-felg-IP2505-Ag-1/ GM-Tg-felg-IP2505-Ag-2; GM-Tg-cang-IP2505-Ag-1/ GM-Tg-cang-IP2505-Ag-2;
GM-Tg-bovg-IP2505-Ag-1/ GM-Tg-bovg-IP2505-Ag-2; GM-Tg-equg-IP2505-Ag-1/ GM-Tg-equg-IP2505-Ag-2
Products Name FOXA2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FOXA2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FOXA2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.