Recombinant multi-species FBLIM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FBLIM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
The Alternative Names of target: FBLIM1,Filamin-binding LIM protein 1,FBLP-1,Migfilin, Mitogen-inducible 2-interacting protein (MIG2-interacting protein),CAL,FBLP1,FBLP-1
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP2495-Ab-1/ GM-Tg-hg-IP2495-Ab-2 | Human FBLIM1 protein | Human |
GM-Tg-rg-IP2495-Ab-1/ GM-Tg-rg-IP2495-Ab-2 | Rat FBLIM1 protein | Rat |
GM-Tg-mg-IP2495-Ab-1/ GM-Tg-mg-IP2495-Ab-2 | Mouse FBLIM1 protein | Mouse |
GM-Tg-cynog-IP2495-Ab-1/ GM-Tg-cynog-IP2495-Ab-2 | Cynomolgus/Rhesus macaque FBLIM1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP2495-Ab-1/ GM-Tg-felg-IP2495-Ab-2 | Feline FBLIM1 protein | Feline |
GM-Tg-cang-IP2495-Ab-1/ GM-Tg-cang-IP2495-Ab-2 | Canine FBLIM1 protein | Canine |
GM-Tg-bovg-IP2495-Ab-1/ GM-Tg-bovg-IP2495-Ab-2 | Bovine FBLIM1 protein | Bovine |
GM-Tg-equg-IP2495-Ab-1/ GM-Tg-equg-IP2495-Ab-2 | Equine FBLIM1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-IP2495-Ab-1/ GM-Tg-hg-IP2495-Ab-2;
GM-Tg-rg-IP2495-Ab-1/ GM-Tg-rg-IP2495-Ab-2;
GM-Tg-mg-IP2495-Ab-1/ GM-Tg-mg-IP2495-Ab-2; GM-Tg-cynog-IP2495-Ab-1/ GM-Tg-cynog-IP2495-Ab-2; GM-Tg-felg-IP2495-Ab-1/ GM-Tg-felg-IP2495-Ab-2; GM-Tg-cang-IP2495-Ab-1/ GM-Tg-cang-IP2495-Ab-2; GM-Tg-bovg-IP2495-Ab-1/ GM-Tg-bovg-IP2495-Ab-2; GM-Tg-equg-IP2495-Ab-1/ GM-Tg-equg-IP2495-Ab-2 |
Products Name | FBLIM1 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | FBLIM1 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FBLIM1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.