Recombinant multi-species CRYGD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRYGD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CACA,CCA3,CCP,CRYG4,CRYGD,CTRCT4,Gamma-D-crystallin,Gamma-crystallin 4,Gamma-crystallin D,PCC,cry-g-D

Target products collectionGo to CRYGD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2439-Ag-1/ GM-Tg-hg-IP2439-Ag-2 Human CRYGD protein Human
GM-Tg-rg-IP2439-Ag-1/ GM-Tg-rg-IP2439-Ag-2 Rat CRYGD protein Rat
GM-Tg-mg-IP2439-Ag-1/ GM-Tg-mg-IP2439-Ag-2 Mouse CRYGD protein Mouse
GM-Tg-cynog-IP2439-Ag-1/ GM-Tg-cynog-IP2439-Ag-2 Cynomolgus/Rhesus macaque CRYGD protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2439-Ag-1/ GM-Tg-felg-IP2439-Ag-2 Feline CRYGD protein Feline
GM-Tg-cang-IP2439-Ag-1/ GM-Tg-cang-IP2439-Ag-2 Canine CRYGD protein Canine
GM-Tg-bovg-IP2439-Ag-1/ GM-Tg-bovg-IP2439-Ag-2 Bovine CRYGD protein Bovine
GM-Tg-equg-IP2439-Ag-1/ GM-Tg-equg-IP2439-Ag-2 Equine CRYGD protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2439-Ag-1/ GM-Tg-hg-IP2439-Ag-2; GM-Tg-rg-IP2439-Ag-1/ GM-Tg-rg-IP2439-Ag-2;
GM-Tg-mg-IP2439-Ag-1/ GM-Tg-mg-IP2439-Ag-2; GM-Tg-cynog-IP2439-Ag-1/ GM-Tg-cynog-IP2439-Ag-2;
GM-Tg-felg-IP2439-Ag-1/ GM-Tg-felg-IP2439-Ag-2; GM-Tg-cang-IP2439-Ag-1/ GM-Tg-cang-IP2439-Ag-2;
GM-Tg-bovg-IP2439-Ag-1/ GM-Tg-bovg-IP2439-Ag-2; GM-Tg-equg-IP2439-Ag-1/ GM-Tg-equg-IP2439-Ag-2
Products Name CRYGD protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CRYGD
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRYGD protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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