Recombinant multi-species CDK5RAP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK5RAP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
The Alternative Names of target: CDK5RAP2,CDK5 regulatory subunit-associated protein 2,CDK5 activator-binding protein C48, Centrosome-associated protein 215,C48,MCPH3,Cep215

Target products collectionGo to CDK5RAP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2419-Ab-1/ GM-Tg-hg-IP2419-Ab-2 Human CDK5RAP2 protein Human
GM-Tg-rg-IP2419-Ab-1/ GM-Tg-rg-IP2419-Ab-2 Rat CDK5RAP2 protein Rat
GM-Tg-mg-IP2419-Ab-1/ GM-Tg-mg-IP2419-Ab-2 Mouse CDK5RAP2 protein Mouse
GM-Tg-cynog-IP2419-Ab-1/ GM-Tg-cynog-IP2419-Ab-2 Cynomolgus/Rhesus macaque CDK5RAP2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2419-Ab-1/ GM-Tg-felg-IP2419-Ab-2 Feline CDK5RAP2 protein Feline
GM-Tg-cang-IP2419-Ab-1/ GM-Tg-cang-IP2419-Ab-2 Canine CDK5RAP2 protein Canine
GM-Tg-bovg-IP2419-Ab-1/ GM-Tg-bovg-IP2419-Ab-2 Bovine CDK5RAP2 protein Bovine
GM-Tg-equg-IP2419-Ab-1/ GM-Tg-equg-IP2419-Ab-2 Equine CDK5RAP2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2419-Ab-1/ GM-Tg-hg-IP2419-Ab-2; GM-Tg-rg-IP2419-Ab-1/ GM-Tg-rg-IP2419-Ab-2;
GM-Tg-mg-IP2419-Ab-1/ GM-Tg-mg-IP2419-Ab-2; GM-Tg-cynog-IP2419-Ab-1/ GM-Tg-cynog-IP2419-Ab-2;
GM-Tg-felg-IP2419-Ab-1/ GM-Tg-felg-IP2419-Ab-2; GM-Tg-cang-IP2419-Ab-1/ GM-Tg-cang-IP2419-Ab-2;
GM-Tg-bovg-IP2419-Ab-1/ GM-Tg-bovg-IP2419-Ab-2; GM-Tg-equg-IP2419-Ab-1/ GM-Tg-equg-IP2419-Ab-2
Products Name CDK5RAP2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CDK5RAP2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK5RAP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.