Recombinant multi-species ARID5B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARID5B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
The Alternative Names of target: 4930580B11,5430435G07Rik,ARID domain-containing protein 5B,ARID5B,AT-rich interactive domain-containing protein 5B,Arid5b,DESRT,Desrt,MRF-2,MRF1-like protein,MRF2,Modulator recognition factor 2 (MRF-2),Mrf2,Mrf2alpha,Mrf2beta

Target products collectionGo to ARID5B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2356-Ag-1/ GM-Tg-hg-IP2356-Ag-2 Human ARID5B protein Human
GM-Tg-rg-IP2356-Ag-1/ GM-Tg-rg-IP2356-Ag-2 Rat ARID5B protein Rat
GM-Tg-mg-IP2356-Ag-1/ GM-Tg-mg-IP2356-Ag-2 Mouse ARID5B protein Mouse
GM-Tg-cynog-IP2356-Ag-1/ GM-Tg-cynog-IP2356-Ag-2 Cynomolgus/Rhesus macaque ARID5B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2356-Ag-1/ GM-Tg-felg-IP2356-Ag-2 Feline ARID5B protein Feline
GM-Tg-cang-IP2356-Ag-1/ GM-Tg-cang-IP2356-Ag-2 Canine ARID5B protein Canine
GM-Tg-bovg-IP2356-Ag-1/ GM-Tg-bovg-IP2356-Ag-2 Bovine ARID5B protein Bovine
GM-Tg-equg-IP2356-Ag-1/ GM-Tg-equg-IP2356-Ag-2 Equine ARID5B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2356-Ag-1/ GM-Tg-hg-IP2356-Ag-2; GM-Tg-rg-IP2356-Ag-1/ GM-Tg-rg-IP2356-Ag-2;
GM-Tg-mg-IP2356-Ag-1/ GM-Tg-mg-IP2356-Ag-2; GM-Tg-cynog-IP2356-Ag-1/ GM-Tg-cynog-IP2356-Ag-2;
GM-Tg-felg-IP2356-Ag-1/ GM-Tg-felg-IP2356-Ag-2; GM-Tg-cang-IP2356-Ag-1/ GM-Tg-cang-IP2356-Ag-2;
GM-Tg-bovg-IP2356-Ag-1/ GM-Tg-bovg-IP2356-Ag-2; GM-Tg-equg-IP2356-Ag-1/ GM-Tg-equg-IP2356-Ag-2
Products Name ARID5B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ARID5B
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARID5B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.