Recombinant multi-species ARHGAP24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARHGAP24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
The Alternative Names of target: 0610025G21Rik,ARHGAP24,Arhgap24,DR-NR#2,FILGAP,Filamin-A-associated RhoGAP (FilGAP),RAC1- and CDC42-specific GTPase-activating protein of 72 kDa (RC-GAP72),RC-GAP72,RCGAP72,Rho GTPase-activating protein 24,Rho-type GTPase-activating protein 24,RhoGAP of 73 kDa,Sarcoma antigen NY-SAR-88,p73,p73RhoGAP
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2349-Ag-1/ GM-Tg-hg-IP2349-Ag-2 | Human ARHGAP24 protein | Human |
| GM-Tg-rg-IP2349-Ag-1/ GM-Tg-rg-IP2349-Ag-2 | Rat ARHGAP24 protein | Rat |
| GM-Tg-mg-IP2349-Ag-1/ GM-Tg-mg-IP2349-Ag-2 | Mouse ARHGAP24 protein | Mouse |
| GM-Tg-cynog-IP2349-Ag-1/ GM-Tg-cynog-IP2349-Ag-2 | Cynomolgus/Rhesus macaque ARHGAP24 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2349-Ag-1/ GM-Tg-felg-IP2349-Ag-2 | Feline ARHGAP24 protein | Feline |
| GM-Tg-cang-IP2349-Ag-1/ GM-Tg-cang-IP2349-Ag-2 | Canine ARHGAP24 protein | Canine |
| GM-Tg-bovg-IP2349-Ag-1/ GM-Tg-bovg-IP2349-Ag-2 | Bovine ARHGAP24 protein | Bovine |
| GM-Tg-equg-IP2349-Ag-1/ GM-Tg-equg-IP2349-Ag-2 | Equine ARHGAP24 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP2349-Ag-1/ GM-Tg-hg-IP2349-Ag-2;
GM-Tg-rg-IP2349-Ag-1/ GM-Tg-rg-IP2349-Ag-2;
GM-Tg-mg-IP2349-Ag-1/ GM-Tg-mg-IP2349-Ag-2; GM-Tg-cynog-IP2349-Ag-1/ GM-Tg-cynog-IP2349-Ag-2; GM-Tg-felg-IP2349-Ag-1/ GM-Tg-felg-IP2349-Ag-2; GM-Tg-cang-IP2349-Ag-1/ GM-Tg-cang-IP2349-Ag-2; GM-Tg-bovg-IP2349-Ag-1/ GM-Tg-bovg-IP2349-Ag-2; GM-Tg-equg-IP2349-Ag-1/ GM-Tg-equg-IP2349-Ag-2 |
| Products Name | ARHGAP24 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ARHGAP24 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARHGAP24 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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myriad domains of biological drug
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strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.