Recombinant multi-species 41701/YWHAQ protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine 41701/YWHAQ protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 14-3-3,14-3-3 protein T-cell,14-3-3 protein tau,14-3-3 protein theta,14-3-3t,1C5,2700028P07Rik,41701,HS1,Protein HS1,YWHAQ,Ywhaq

Target products collectionGo to 41701/YWHAQ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2293-Ag-1/ GM-Tg-hg-IP2293-Ag-2 Human 41701/YWHAQ protein Human
GM-Tg-rg-IP2293-Ag-1/ GM-Tg-rg-IP2293-Ag-2 Rat 41701/YWHAQ protein Rat
GM-Tg-mg-IP2293-Ag-1/ GM-Tg-mg-IP2293-Ag-2 Mouse 41701/YWHAQ protein Mouse
GM-Tg-cynog-IP2293-Ag-1/ GM-Tg-cynog-IP2293-Ag-2 Cynomolgus/Rhesus macaque 41701/YWHAQ protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2293-Ag-1/ GM-Tg-felg-IP2293-Ag-2 Feline 41701/YWHAQ protein Feline
GM-Tg-cang-IP2293-Ag-1/ GM-Tg-cang-IP2293-Ag-2 Canine 41701/YWHAQ protein Canine
GM-Tg-bovg-IP2293-Ag-1/ GM-Tg-bovg-IP2293-Ag-2 Bovine 41701/YWHAQ protein Bovine
GM-Tg-equg-IP2293-Ag-1/ GM-Tg-equg-IP2293-Ag-2 Equine 41701/YWHAQ protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2293-Ag-1/ GM-Tg-hg-IP2293-Ag-2; GM-Tg-rg-IP2293-Ag-1/ GM-Tg-rg-IP2293-Ag-2;
GM-Tg-mg-IP2293-Ag-1/ GM-Tg-mg-IP2293-Ag-2; GM-Tg-cynog-IP2293-Ag-1/ GM-Tg-cynog-IP2293-Ag-2;
GM-Tg-felg-IP2293-Ag-1/ GM-Tg-felg-IP2293-Ag-2; GM-Tg-cang-IP2293-Ag-1/ GM-Tg-cang-IP2293-Ag-2;
GM-Tg-bovg-IP2293-Ag-1/ GM-Tg-bovg-IP2293-Ag-2; GM-Tg-equg-IP2293-Ag-1/ GM-Tg-equg-IP2293-Ag-2
Products Name 41701/YWHAQ protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name 41701/YWHAQ
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine 41701/YWHAQ protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.