Recombinant multi-species USP19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine USP19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
The Alternative Names of target: 8430421I07Rik,Deubiquitinating enzyme 19,USP19,Ubiquitin carboxyl-terminal hydrolase 19,Ubiquitin thioesterase 19,Ubiquitin-specific-processing protease 19,Usp19,ZMYND9,Zinc finger MYND domain-containing protein 9,Zmynd9
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP2255-Ag-1/ GM-Tg-hg-IP2255-Ag-2 | Human USP19 protein | Human |
GM-Tg-rg-IP2255-Ag-1/ GM-Tg-rg-IP2255-Ag-2 | Rat USP19 protein | Rat |
GM-Tg-mg-IP2255-Ag-1/ GM-Tg-mg-IP2255-Ag-2 | Mouse USP19 protein | Mouse |
GM-Tg-cynog-IP2255-Ag-1/ GM-Tg-cynog-IP2255-Ag-2 | Cynomolgus/Rhesus macaque USP19 protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP2255-Ag-1/ GM-Tg-felg-IP2255-Ag-2 | Feline USP19 protein | Feline |
GM-Tg-cang-IP2255-Ag-1/ GM-Tg-cang-IP2255-Ag-2 | Canine USP19 protein | Canine |
GM-Tg-bovg-IP2255-Ag-1/ GM-Tg-bovg-IP2255-Ag-2 | Bovine USP19 protein | Bovine |
GM-Tg-equg-IP2255-Ag-1/ GM-Tg-equg-IP2255-Ag-2 | Equine USP19 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-IP2255-Ag-1/ GM-Tg-hg-IP2255-Ag-2;
GM-Tg-rg-IP2255-Ag-1/ GM-Tg-rg-IP2255-Ag-2;
GM-Tg-mg-IP2255-Ag-1/ GM-Tg-mg-IP2255-Ag-2; GM-Tg-cynog-IP2255-Ag-1/ GM-Tg-cynog-IP2255-Ag-2; GM-Tg-felg-IP2255-Ag-1/ GM-Tg-felg-IP2255-Ag-2; GM-Tg-cang-IP2255-Ag-1/ GM-Tg-cang-IP2255-Ag-2; GM-Tg-bovg-IP2255-Ag-1/ GM-Tg-bovg-IP2255-Ag-2; GM-Tg-equg-IP2255-Ag-1/ GM-Tg-equg-IP2255-Ag-2 |
Products Name | USP19 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | USP19 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine USP19 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.