Recombinant multi-species Beta/TUBB3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Beta/TUBB3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]
The Alternative Names of target: 3200002H15Rik,Beta,CDCBM,CDCBM1,CFEOM3,CFEOM3A,FEOM3,M(beta)3,M(beta)6,TUBB3,TUBB4,Tubb3,Tubulin beta-3 chain,Tubulin beta-4 chain,Tubulin beta-III,beta-4

Target products collectionGo to Beta/TUBB3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2208-Ag-1/ GM-Tg-hg-IP2208-Ag-2 Human Beta/TUBB3 protein Human
GM-Tg-rg-IP2208-Ag-1/ GM-Tg-rg-IP2208-Ag-2 Rat Beta/TUBB3 protein Rat
GM-Tg-mg-IP2208-Ag-1/ GM-Tg-mg-IP2208-Ag-2 Mouse Beta/TUBB3 protein Mouse
GM-Tg-cynog-IP2208-Ag-1/ GM-Tg-cynog-IP2208-Ag-2 Cynomolgus/Rhesus macaque Beta/TUBB3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2208-Ag-1/ GM-Tg-felg-IP2208-Ag-2 Feline Beta/TUBB3 protein Feline
GM-Tg-cang-IP2208-Ag-1/ GM-Tg-cang-IP2208-Ag-2 Canine Beta/TUBB3 protein Canine
GM-Tg-bovg-IP2208-Ag-1/ GM-Tg-bovg-IP2208-Ag-2 Bovine Beta/TUBB3 protein Bovine
GM-Tg-equg-IP2208-Ag-1/ GM-Tg-equg-IP2208-Ag-2 Equine Beta/TUBB3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2208-Ag-1/ GM-Tg-hg-IP2208-Ag-2; GM-Tg-rg-IP2208-Ag-1/ GM-Tg-rg-IP2208-Ag-2;
GM-Tg-mg-IP2208-Ag-1/ GM-Tg-mg-IP2208-Ag-2; GM-Tg-cynog-IP2208-Ag-1/ GM-Tg-cynog-IP2208-Ag-2;
GM-Tg-felg-IP2208-Ag-1/ GM-Tg-felg-IP2208-Ag-2; GM-Tg-cang-IP2208-Ag-1/ GM-Tg-cang-IP2208-Ag-2;
GM-Tg-bovg-IP2208-Ag-1/ GM-Tg-bovg-IP2208-Ag-2; GM-Tg-equg-IP2208-Ag-1/ GM-Tg-equg-IP2208-Ag-2
Products Name Beta/TUBB3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Beta/TUBB3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Beta/TUBB3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.