Recombinant multi-species TMPRSS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMPRSS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
The Alternative Names of target: DFNB10,DFNB8,ECHOS1,Serine protease TADG-12,TADG12,TMPRSS3,Tmprss3,Transmembrane protease serine 3,Tumor-associated differentially-expressed gene 12 protein

Target products collectionGo to TMPRSS3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2147-Ag-1/ GM-Tg-hg-IP2147-Ag-2 Human TMPRSS3 protein Human
GM-Tg-rg-IP2147-Ag-1/ GM-Tg-rg-IP2147-Ag-2 Rat TMPRSS3 protein Rat
GM-Tg-mg-IP2147-Ag-1/ GM-Tg-mg-IP2147-Ag-2 Mouse TMPRSS3 protein Mouse
GM-Tg-cynog-IP2147-Ag-1/ GM-Tg-cynog-IP2147-Ag-2 Cynomolgus/Rhesus macaque TMPRSS3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2147-Ag-1/ GM-Tg-felg-IP2147-Ag-2 Feline TMPRSS3 protein Feline
GM-Tg-cang-IP2147-Ag-1/ GM-Tg-cang-IP2147-Ag-2 Canine TMPRSS3 protein Canine
GM-Tg-bovg-IP2147-Ag-1/ GM-Tg-bovg-IP2147-Ag-2 Bovine TMPRSS3 protein Bovine
GM-Tg-equg-IP2147-Ag-1/ GM-Tg-equg-IP2147-Ag-2 Equine TMPRSS3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2147-Ag-1/ GM-Tg-hg-IP2147-Ag-2; GM-Tg-rg-IP2147-Ag-1/ GM-Tg-rg-IP2147-Ag-2;
GM-Tg-mg-IP2147-Ag-1/ GM-Tg-mg-IP2147-Ag-2; GM-Tg-cynog-IP2147-Ag-1/ GM-Tg-cynog-IP2147-Ag-2;
GM-Tg-felg-IP2147-Ag-1/ GM-Tg-felg-IP2147-Ag-2; GM-Tg-cang-IP2147-Ag-1/ GM-Tg-cang-IP2147-Ag-2;
GM-Tg-bovg-IP2147-Ag-1/ GM-Tg-bovg-IP2147-Ag-2; GM-Tg-equg-IP2147-Ag-1/ GM-Tg-equg-IP2147-Ag-2
Products Name TMPRSS3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TMPRSS3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMPRSS3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.