Recombinant multi-species TMEM165 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMEM165 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a predicted transmembrane protein with a perinuclear Golgi-like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation, type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
The Alternative Names of target: TMEM165,Putative divalent cation/proton antiporter TMEM165,Transmembrane protein 165, Transmembrane protein PT27, Transmembrane protein TPARL,FT27,GDT1,CDG2K,TPARL,TMPT27,SLC64A1

Target products collectionGo to TMEM165 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2004-Ab-1/ GM-Tg-hg-IP2004-Ab-2 Human TMEM165 protein Human
GM-Tg-rg-IP2004-Ab-1/ GM-Tg-rg-IP2004-Ab-2 Rat TMEM165 protein Rat
GM-Tg-mg-IP2004-Ab-1/ GM-Tg-mg-IP2004-Ab-2 Mouse TMEM165 protein Mouse
GM-Tg-cynog-IP2004-Ab-1/ GM-Tg-cynog-IP2004-Ab-2 Cynomolgus/Rhesus macaque TMEM165 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2004-Ab-1/ GM-Tg-felg-IP2004-Ab-2 Feline TMEM165 protein Feline
GM-Tg-cang-IP2004-Ab-1/ GM-Tg-cang-IP2004-Ab-2 Canine TMEM165 protein Canine
GM-Tg-bovg-IP2004-Ab-1/ GM-Tg-bovg-IP2004-Ab-2 Bovine TMEM165 protein Bovine
GM-Tg-equg-IP2004-Ab-1/ GM-Tg-equg-IP2004-Ab-2 Equine TMEM165 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2004-Ab-1/ GM-Tg-hg-IP2004-Ab-2; GM-Tg-rg-IP2004-Ab-1/ GM-Tg-rg-IP2004-Ab-2;
GM-Tg-mg-IP2004-Ab-1/ GM-Tg-mg-IP2004-Ab-2; GM-Tg-cynog-IP2004-Ab-1/ GM-Tg-cynog-IP2004-Ab-2;
GM-Tg-felg-IP2004-Ab-1/ GM-Tg-felg-IP2004-Ab-2; GM-Tg-cang-IP2004-Ab-1/ GM-Tg-cang-IP2004-Ab-2;
GM-Tg-bovg-IP2004-Ab-1/ GM-Tg-bovg-IP2004-Ab-2; GM-Tg-equg-IP2004-Ab-1/ GM-Tg-equg-IP2004-Ab-2
Products Name TMEM165 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TMEM165
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMEM165 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.