Recombinant multi-species TAP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TAP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]
The Alternative Names of target: TAP2,Antigen peptide transporter 2,APT2,ATP-binding cassette sub-family B member 3, Peptide supply factor 2, Peptide transporter PSF2 (PSF-2), Peptide transporter TAP2, Peptide transporter involved in antigen processing 2, Really interesting new gene 11 protein (RING11),APT2,PSF2,ABC18,ABCB3,PSF-2,MHC1D2,RING11,D6S217E

Target products collectionGo to TAP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1881-Ab-1/ GM-Tg-hg-IP1881-Ab-2 Human TAP2 protein Human
GM-Tg-rg-IP1881-Ab-1/ GM-Tg-rg-IP1881-Ab-2 Rat TAP2 protein Rat
GM-Tg-mg-IP1881-Ab-1/ GM-Tg-mg-IP1881-Ab-2 Mouse TAP2 protein Mouse
GM-Tg-cynog-IP1881-Ab-1/ GM-Tg-cynog-IP1881-Ab-2 Cynomolgus/Rhesus macaque TAP2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1881-Ab-1/ GM-Tg-felg-IP1881-Ab-2 Feline TAP2 protein Feline
GM-Tg-cang-IP1881-Ab-1/ GM-Tg-cang-IP1881-Ab-2 Canine TAP2 protein Canine
GM-Tg-bovg-IP1881-Ab-1/ GM-Tg-bovg-IP1881-Ab-2 Bovine TAP2 protein Bovine
GM-Tg-equg-IP1881-Ab-1/ GM-Tg-equg-IP1881-Ab-2 Equine TAP2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1881-Ab-1/ GM-Tg-hg-IP1881-Ab-2; GM-Tg-rg-IP1881-Ab-1/ GM-Tg-rg-IP1881-Ab-2;
GM-Tg-mg-IP1881-Ab-1/ GM-Tg-mg-IP1881-Ab-2; GM-Tg-cynog-IP1881-Ab-1/ GM-Tg-cynog-IP1881-Ab-2;
GM-Tg-felg-IP1881-Ab-1/ GM-Tg-felg-IP1881-Ab-2; GM-Tg-cang-IP1881-Ab-1/ GM-Tg-cang-IP1881-Ab-2;
GM-Tg-bovg-IP1881-Ab-1/ GM-Tg-bovg-IP1881-Ab-2; GM-Tg-equg-IP1881-Ab-1/ GM-Tg-equg-IP1881-Ab-2
Products Name TAP2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TAP2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TAP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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