Recombinant multi-species ST8SIA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ST8SIA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]
The Alternative Names of target: ST8SIA1,Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase,Alpha-2,8-sialyltransferase 8A, Ganglioside GD3 synthase, Ganglioside GT3 synthase, Sialyltransferase 8A (SIAT8-A), Sialyltransferase St8Sia I (ST8SiaI),GD3S,SIAT8,SIAT8A,SIAT8-A,ST8SiaI

Target products collectionGo to ST8SIA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1835-Ab-1/ GM-Tg-hg-IP1835-Ab-2 Human ST8SIA1 protein Human
GM-Tg-rg-IP1835-Ab-1/ GM-Tg-rg-IP1835-Ab-2 Rat ST8SIA1 protein Rat
GM-Tg-mg-IP1835-Ab-1/ GM-Tg-mg-IP1835-Ab-2 Mouse ST8SIA1 protein Mouse
GM-Tg-cynog-IP1835-Ab-1/ GM-Tg-cynog-IP1835-Ab-2 Cynomolgus/Rhesus macaque ST8SIA1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1835-Ab-1/ GM-Tg-felg-IP1835-Ab-2 Feline ST8SIA1 protein Feline
GM-Tg-cang-IP1835-Ab-1/ GM-Tg-cang-IP1835-Ab-2 Canine ST8SIA1 protein Canine
GM-Tg-bovg-IP1835-Ab-1/ GM-Tg-bovg-IP1835-Ab-2 Bovine ST8SIA1 protein Bovine
GM-Tg-equg-IP1835-Ab-1/ GM-Tg-equg-IP1835-Ab-2 Equine ST8SIA1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1835-Ab-1/ GM-Tg-hg-IP1835-Ab-2; GM-Tg-rg-IP1835-Ab-1/ GM-Tg-rg-IP1835-Ab-2;
GM-Tg-mg-IP1835-Ab-1/ GM-Tg-mg-IP1835-Ab-2; GM-Tg-cynog-IP1835-Ab-1/ GM-Tg-cynog-IP1835-Ab-2;
GM-Tg-felg-IP1835-Ab-1/ GM-Tg-felg-IP1835-Ab-2; GM-Tg-cang-IP1835-Ab-1/ GM-Tg-cang-IP1835-Ab-2;
GM-Tg-bovg-IP1835-Ab-1/ GM-Tg-bovg-IP1835-Ab-2; GM-Tg-equg-IP1835-Ab-1/ GM-Tg-equg-IP1835-Ab-2
Products Name ST8SIA1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ST8SIA1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ST8SIA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.