Recombinant multi-species ST6GALNAC4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ST6GALNAC4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. Readthrough transcripts exist for this gene and the downstream ST6GALNAC6 gene. [provided by RefSeq, Jan 2022]
The Alternative Names of target: ST6GALNAC4,Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase,NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase, ST6GalNAc IV (ST6GalNAcIV), Sialyltransferase 3C (SIAT3-C), Sialyltransferase 7D (SIAT7-D),IV,SIAT3C,SIAT7D,SIAT3-C,SIAT7-D,ST6GalNAc,ST6GALNACIV
Go
to ST6GALNAC4 products collection
>>
(antibodies,
antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP1832-Ab-1/ GM-Tg-hg-IP1832-Ab-2 | Human ST6GALNAC4 protein | Human |
GM-Tg-rg-IP1832-Ab-1/ GM-Tg-rg-IP1832-Ab-2 | Rat ST6GALNAC4 protein | Rat |
GM-Tg-mg-IP1832-Ab-1/ GM-Tg-mg-IP1832-Ab-2 | Mouse ST6GALNAC4 protein | Mouse |
GM-Tg-cynog-IP1832-Ab-1/ GM-Tg-cynog-IP1832-Ab-2 | Cynomolgus/Rhesus macaque ST6GALNAC4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP1832-Ab-1/ GM-Tg-felg-IP1832-Ab-2 | Feline ST6GALNAC4 protein | Feline |
GM-Tg-cang-IP1832-Ab-1/ GM-Tg-cang-IP1832-Ab-2 | Canine ST6GALNAC4 protein | Canine |
GM-Tg-bovg-IP1832-Ab-1/ GM-Tg-bovg-IP1832-Ab-2 | Bovine ST6GALNAC4 protein | Bovine |
GM-Tg-equg-IP1832-Ab-1/ GM-Tg-equg-IP1832-Ab-2 | Equine ST6GALNAC4 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-IP1832-Ab-1/ GM-Tg-hg-IP1832-Ab-2;
GM-Tg-rg-IP1832-Ab-1/ GM-Tg-rg-IP1832-Ab-2;
GM-Tg-mg-IP1832-Ab-1/ GM-Tg-mg-IP1832-Ab-2; GM-Tg-cynog-IP1832-Ab-1/ GM-Tg-cynog-IP1832-Ab-2; GM-Tg-felg-IP1832-Ab-1/ GM-Tg-felg-IP1832-Ab-2; GM-Tg-cang-IP1832-Ab-1/ GM-Tg-cang-IP1832-Ab-2; GM-Tg-bovg-IP1832-Ab-1/ GM-Tg-bovg-IP1832-Ab-2; GM-Tg-equg-IP1832-Ab-1/ GM-Tg-equg-IP1832-Ab-2 |
Products Name | ST6GALNAC4 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | ST6GALNAC4 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ST6GALNAC4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.