Recombinant multi-species ST6GALNAC4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ST6GALNAC4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. Readthrough transcripts exist for this gene and the downstream ST6GALNAC6 gene. [provided by RefSeq, Jan 2022]
The Alternative Names of target: ST6GALNAC4,Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase,NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase, ST6GalNAc IV (ST6GalNAcIV), Sialyltransferase 3C (SIAT3-C), Sialyltransferase 7D (SIAT7-D),IV,SIAT3C,SIAT7D,SIAT3-C,SIAT7-D,ST6GalNAc,ST6GALNACIV

Target products collectionGo to ST6GALNAC4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1832-Ab-1/ GM-Tg-hg-IP1832-Ab-2 Human ST6GALNAC4 protein Human
GM-Tg-rg-IP1832-Ab-1/ GM-Tg-rg-IP1832-Ab-2 Rat ST6GALNAC4 protein Rat
GM-Tg-mg-IP1832-Ab-1/ GM-Tg-mg-IP1832-Ab-2 Mouse ST6GALNAC4 protein Mouse
GM-Tg-cynog-IP1832-Ab-1/ GM-Tg-cynog-IP1832-Ab-2 Cynomolgus/Rhesus macaque ST6GALNAC4 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1832-Ab-1/ GM-Tg-felg-IP1832-Ab-2 Feline ST6GALNAC4 protein Feline
GM-Tg-cang-IP1832-Ab-1/ GM-Tg-cang-IP1832-Ab-2 Canine ST6GALNAC4 protein Canine
GM-Tg-bovg-IP1832-Ab-1/ GM-Tg-bovg-IP1832-Ab-2 Bovine ST6GALNAC4 protein Bovine
GM-Tg-equg-IP1832-Ab-1/ GM-Tg-equg-IP1832-Ab-2 Equine ST6GALNAC4 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1832-Ab-1/ GM-Tg-hg-IP1832-Ab-2; GM-Tg-rg-IP1832-Ab-1/ GM-Tg-rg-IP1832-Ab-2;
GM-Tg-mg-IP1832-Ab-1/ GM-Tg-mg-IP1832-Ab-2; GM-Tg-cynog-IP1832-Ab-1/ GM-Tg-cynog-IP1832-Ab-2;
GM-Tg-felg-IP1832-Ab-1/ GM-Tg-felg-IP1832-Ab-2; GM-Tg-cang-IP1832-Ab-1/ GM-Tg-cang-IP1832-Ab-2;
GM-Tg-bovg-IP1832-Ab-1/ GM-Tg-bovg-IP1832-Ab-2; GM-Tg-equg-IP1832-Ab-1/ GM-Tg-equg-IP1832-Ab-2
Products Name ST6GALNAC4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ST6GALNAC4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ST6GALNAC4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.