Recombinant multi-species SLC18A1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SLC18A1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]
The Alternative Names of target: 4832416I10Rik,CGAT,Chromaffin granule amine transporter,SLC18A1,Slc18a1,Solute carrier family 18 member 1,VAT1,VMAT-1,VMAT1,Vat1,Vesicular amine transporter 1 (VAT1),Vmat1

Target products collectionGo to SLC18A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1657-Ag-1/ GM-Tg-hg-IP1657-Ag-2 Human SLC18A1 protein Human
GM-Tg-rg-IP1657-Ag-1/ GM-Tg-rg-IP1657-Ag-2 Rat SLC18A1 protein Rat
GM-Tg-mg-IP1657-Ag-1/ GM-Tg-mg-IP1657-Ag-2 Mouse SLC18A1 protein Mouse
GM-Tg-cynog-IP1657-Ag-1/ GM-Tg-cynog-IP1657-Ag-2 Cynomolgus/Rhesus macaque SLC18A1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1657-Ag-1/ GM-Tg-felg-IP1657-Ag-2 Feline SLC18A1 protein Feline
GM-Tg-cang-IP1657-Ag-1/ GM-Tg-cang-IP1657-Ag-2 Canine SLC18A1 protein Canine
GM-Tg-bovg-IP1657-Ag-1/ GM-Tg-bovg-IP1657-Ag-2 Bovine SLC18A1 protein Bovine
GM-Tg-equg-IP1657-Ag-1/ GM-Tg-equg-IP1657-Ag-2 Equine SLC18A1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1657-Ag-1/ GM-Tg-hg-IP1657-Ag-2; GM-Tg-rg-IP1657-Ag-1/ GM-Tg-rg-IP1657-Ag-2;
GM-Tg-mg-IP1657-Ag-1/ GM-Tg-mg-IP1657-Ag-2; GM-Tg-cynog-IP1657-Ag-1/ GM-Tg-cynog-IP1657-Ag-2;
GM-Tg-felg-IP1657-Ag-1/ GM-Tg-felg-IP1657-Ag-2; GM-Tg-cang-IP1657-Ag-1/ GM-Tg-cang-IP1657-Ag-2;
GM-Tg-bovg-IP1657-Ag-1/ GM-Tg-bovg-IP1657-Ag-2; GM-Tg-equg-IP1657-Ag-1/ GM-Tg-equg-IP1657-Ag-2
Products Name SLC18A1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SLC18A1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SLC18A1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.