Recombinant multi-species SCN10A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SCN10A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
The Alternative Names of target: FEPS2,Na(V)1.8,Nav1.8,PN3,Peripheral nerve sodium channel 3 (PN3,SCN10A,SNS,Scn10a,Sodium channel protein type 10 subunit alpha,Sodium channel protein type X subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.8,hPN3)

Target products collectionGo to SCN10A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1586-Ag-1/ GM-Tg-hg-IP1586-Ag-2 Human SCN10A protein Human
GM-Tg-rg-IP1586-Ag-1/ GM-Tg-rg-IP1586-Ag-2 Rat SCN10A protein Rat
GM-Tg-mg-IP1586-Ag-1/ GM-Tg-mg-IP1586-Ag-2 Mouse SCN10A protein Mouse
GM-Tg-cynog-IP1586-Ag-1/ GM-Tg-cynog-IP1586-Ag-2 Cynomolgus/Rhesus macaque SCN10A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1586-Ag-1/ GM-Tg-felg-IP1586-Ag-2 Feline SCN10A protein Feline
GM-Tg-cang-IP1586-Ag-1/ GM-Tg-cang-IP1586-Ag-2 Canine SCN10A protein Canine
GM-Tg-bovg-IP1586-Ag-1/ GM-Tg-bovg-IP1586-Ag-2 Bovine SCN10A protein Bovine
GM-Tg-equg-IP1586-Ag-1/ GM-Tg-equg-IP1586-Ag-2 Equine SCN10A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1586-Ag-1/ GM-Tg-hg-IP1586-Ag-2; GM-Tg-rg-IP1586-Ag-1/ GM-Tg-rg-IP1586-Ag-2;
GM-Tg-mg-IP1586-Ag-1/ GM-Tg-mg-IP1586-Ag-2; GM-Tg-cynog-IP1586-Ag-1/ GM-Tg-cynog-IP1586-Ag-2;
GM-Tg-felg-IP1586-Ag-1/ GM-Tg-felg-IP1586-Ag-2; GM-Tg-cang-IP1586-Ag-1/ GM-Tg-cang-IP1586-Ag-2;
GM-Tg-bovg-IP1586-Ag-1/ GM-Tg-bovg-IP1586-Ag-2; GM-Tg-equg-IP1586-Ag-1/ GM-Tg-equg-IP1586-Ag-2
Products Name SCN10A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SCN10A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SCN10A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.