Recombinant multi-species RNF130 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF130 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
The Alternative Names of target: 2510042A13Rik,E3 ubiquitin-protein ligase RNF130,G1RP,G1RZFP,G1rp,GOLIATH,GP,Goliath homolog (H-Goliath),RING finger protein 130,RING-type E3 ubiquitin transferase RNF130,RNF130,Rnf130
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1505-Ag-1/ GM-Tg-hg-IP1505-Ag-2 | Human RNF130 protein | Human |
| GM-Tg-rg-IP1505-Ag-1/ GM-Tg-rg-IP1505-Ag-2 | Rat RNF130 protein | Rat |
| GM-Tg-mg-IP1505-Ag-1/ GM-Tg-mg-IP1505-Ag-2 | Mouse RNF130 protein | Mouse |
| GM-Tg-cynog-IP1505-Ag-1/ GM-Tg-cynog-IP1505-Ag-2 | Cynomolgus/Rhesus macaque RNF130 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1505-Ag-1/ GM-Tg-felg-IP1505-Ag-2 | Feline RNF130 protein | Feline |
| GM-Tg-cang-IP1505-Ag-1/ GM-Tg-cang-IP1505-Ag-2 | Canine RNF130 protein | Canine |
| GM-Tg-bovg-IP1505-Ag-1/ GM-Tg-bovg-IP1505-Ag-2 | Bovine RNF130 protein | Bovine |
| GM-Tg-equg-IP1505-Ag-1/ GM-Tg-equg-IP1505-Ag-2 | Equine RNF130 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP1505-Ag-1/ GM-Tg-hg-IP1505-Ag-2;
GM-Tg-rg-IP1505-Ag-1/ GM-Tg-rg-IP1505-Ag-2;
GM-Tg-mg-IP1505-Ag-1/ GM-Tg-mg-IP1505-Ag-2; GM-Tg-cynog-IP1505-Ag-1/ GM-Tg-cynog-IP1505-Ag-2; GM-Tg-felg-IP1505-Ag-1/ GM-Tg-felg-IP1505-Ag-2; GM-Tg-cang-IP1505-Ag-1/ GM-Tg-cang-IP1505-Ag-2; GM-Tg-bovg-IP1505-Ag-1/ GM-Tg-bovg-IP1505-Ag-2; GM-Tg-equg-IP1505-Ag-1/ GM-Tg-equg-IP1505-Ag-2 |
| Products Name | RNF130 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RNF130 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF130 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.