Recombinant multi-species RNF128 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF128 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1300002C13Rik,E3 ubiquitin-protein ligase RNF128,GRAIL,Gene related to anergy in lymphocytes protein (GRAIL),Greul1,RGD1566282,RING finger protein 128,RING-type E3 ubiquitin transferase RNF128,RNF128,Rnf128

Target products collectionGo to RNF128 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1504-Ag-1/ GM-Tg-hg-IP1504-Ag-2 Human RNF128 protein Human
GM-Tg-rg-IP1504-Ag-1/ GM-Tg-rg-IP1504-Ag-2 Rat RNF128 protein Rat
GM-Tg-mg-IP1504-Ag-1/ GM-Tg-mg-IP1504-Ag-2 Mouse RNF128 protein Mouse
GM-Tg-cynog-IP1504-Ag-1/ GM-Tg-cynog-IP1504-Ag-2 Cynomolgus/Rhesus macaque RNF128 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1504-Ag-1/ GM-Tg-felg-IP1504-Ag-2 Feline RNF128 protein Feline
GM-Tg-cang-IP1504-Ag-1/ GM-Tg-cang-IP1504-Ag-2 Canine RNF128 protein Canine
GM-Tg-bovg-IP1504-Ag-1/ GM-Tg-bovg-IP1504-Ag-2 Bovine RNF128 protein Bovine
GM-Tg-equg-IP1504-Ag-1/ GM-Tg-equg-IP1504-Ag-2 Equine RNF128 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1504-Ag-1/ GM-Tg-hg-IP1504-Ag-2; GM-Tg-rg-IP1504-Ag-1/ GM-Tg-rg-IP1504-Ag-2;
GM-Tg-mg-IP1504-Ag-1/ GM-Tg-mg-IP1504-Ag-2; GM-Tg-cynog-IP1504-Ag-1/ GM-Tg-cynog-IP1504-Ag-2;
GM-Tg-felg-IP1504-Ag-1/ GM-Tg-felg-IP1504-Ag-2; GM-Tg-cang-IP1504-Ag-1/ GM-Tg-cang-IP1504-Ag-2;
GM-Tg-bovg-IP1504-Ag-1/ GM-Tg-bovg-IP1504-Ag-2; GM-Tg-equg-IP1504-Ag-1/ GM-Tg-equg-IP1504-Ag-2
Products Name RNF128 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RNF128
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF128 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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