Recombinant multi-species CDC42 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDC42 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
The Alternative Names of target: CDC42,CDC42Hs,Cdc42,Cell division control protein 42 homolog,G25K,G25K GTP-binding protein,TKS

Target products collectionGo to CDC42 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP14024-Ag-1/ GM-Tg-hg-IP14024-Ag-2 Human CDC42 protein Human
GM-Tg-rg-IP14024-Ag-1/ GM-Tg-rg-IP14024-Ag-2 Rat CDC42 protein Rat
GM-Tg-mg-IP14024-Ag-1/ GM-Tg-mg-IP14024-Ag-2 Mouse CDC42 protein Mouse
GM-Tg-cynog-IP14024-Ag-1/ GM-Tg-cynog-IP14024-Ag-2 Cynomolgus/Rhesus macaque CDC42 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP14024-Ag-1/ GM-Tg-felg-IP14024-Ag-2 Feline CDC42 protein Feline
GM-Tg-cang-IP14024-Ag-1/ GM-Tg-cang-IP14024-Ag-2 Canine CDC42 protein Canine
GM-Tg-bovg-IP14024-Ag-1/ GM-Tg-bovg-IP14024-Ag-2 Bovine CDC42 protein Bovine
GM-Tg-equg-IP14024-Ag-1/ GM-Tg-equg-IP14024-Ag-2 Equine CDC42 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP14024-Ag-1/ GM-Tg-hg-IP14024-Ag-2; GM-Tg-rg-IP14024-Ag-1/ GM-Tg-rg-IP14024-Ag-2;
GM-Tg-mg-IP14024-Ag-1/ GM-Tg-mg-IP14024-Ag-2; GM-Tg-cynog-IP14024-Ag-1/ GM-Tg-cynog-IP14024-Ag-2;
GM-Tg-felg-IP14024-Ag-1/ GM-Tg-felg-IP14024-Ag-2; GM-Tg-cang-IP14024-Ag-1/ GM-Tg-cang-IP14024-Ag-2;
GM-Tg-bovg-IP14024-Ag-1/ GM-Tg-bovg-IP14024-Ag-2; GM-Tg-equg-IP14024-Ag-1/ GM-Tg-equg-IP14024-Ag-2
Products Name CDC42 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CDC42
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDC42 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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