Recombinant multi-species RNF40 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF40 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
The Alternative Names of target: 95 kDa retinoblastoma-associated protein (RBP95),BRE1-B,BRE1B,E3 ubiquitin-protein ligase BRE1B,RBP95,RING finger protein 40,RING-type E3 ubiquitin transferase BRE1B,RNF40,Rnf40,STARING,mKIAA0661
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP13933-Ag-1/ GM-Tg-hg-IP13933-Ag-2 | Human RNF40 protein | Human |
| GM-Tg-rg-IP13933-Ag-1/ GM-Tg-rg-IP13933-Ag-2 | Rat RNF40 protein | Rat |
| GM-Tg-mg-IP13933-Ag-1/ GM-Tg-mg-IP13933-Ag-2 | Mouse RNF40 protein | Mouse |
| GM-Tg-cynog-IP13933-Ag-1/ GM-Tg-cynog-IP13933-Ag-2 | Cynomolgus/Rhesus macaque RNF40 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP13933-Ag-1/ GM-Tg-felg-IP13933-Ag-2 | Feline RNF40 protein | Feline |
| GM-Tg-cang-IP13933-Ag-1/ GM-Tg-cang-IP13933-Ag-2 | Canine RNF40 protein | Canine |
| GM-Tg-bovg-IP13933-Ag-1/ GM-Tg-bovg-IP13933-Ag-2 | Bovine RNF40 protein | Bovine |
| GM-Tg-equg-IP13933-Ag-1/ GM-Tg-equg-IP13933-Ag-2 | Equine RNF40 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP13933-Ag-1/ GM-Tg-hg-IP13933-Ag-2;
GM-Tg-rg-IP13933-Ag-1/ GM-Tg-rg-IP13933-Ag-2;
GM-Tg-mg-IP13933-Ag-1/ GM-Tg-mg-IP13933-Ag-2; GM-Tg-cynog-IP13933-Ag-1/ GM-Tg-cynog-IP13933-Ag-2; GM-Tg-felg-IP13933-Ag-1/ GM-Tg-felg-IP13933-Ag-2; GM-Tg-cang-IP13933-Ag-1/ GM-Tg-cang-IP13933-Ag-2; GM-Tg-bovg-IP13933-Ag-1/ GM-Tg-bovg-IP13933-Ag-2; GM-Tg-equg-IP13933-Ag-1/ GM-Tg-equg-IP13933-Ag-2 |
| Products Name | RNF40 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RNF40 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF40 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.