Recombinant multi-species IST1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IST1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
The Alternative Names of target: 2400003C14Rik,CHMP8,Charged multivesicular body protein 8 (CHMP8),IST1,IST1 homolog,Ist1,KIAA0174,OLC1,Putative MAPK-activating protein PM28,RGD1307799,hIST1,mKIAA0174

Target products collectionGo to IST1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13928-Ag-1/ GM-Tg-hg-IP13928-Ag-2 Human IST1 protein Human
GM-Tg-rg-IP13928-Ag-1/ GM-Tg-rg-IP13928-Ag-2 Rat IST1 protein Rat
GM-Tg-mg-IP13928-Ag-1/ GM-Tg-mg-IP13928-Ag-2 Mouse IST1 protein Mouse
GM-Tg-cynog-IP13928-Ag-1/ GM-Tg-cynog-IP13928-Ag-2 Cynomolgus/Rhesus macaque IST1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13928-Ag-1/ GM-Tg-felg-IP13928-Ag-2 Feline IST1 protein Feline
GM-Tg-cang-IP13928-Ag-1/ GM-Tg-cang-IP13928-Ag-2 Canine IST1 protein Canine
GM-Tg-bovg-IP13928-Ag-1/ GM-Tg-bovg-IP13928-Ag-2 Bovine IST1 protein Bovine
GM-Tg-equg-IP13928-Ag-1/ GM-Tg-equg-IP13928-Ag-2 Equine IST1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13928-Ag-1/ GM-Tg-hg-IP13928-Ag-2; GM-Tg-rg-IP13928-Ag-1/ GM-Tg-rg-IP13928-Ag-2;
GM-Tg-mg-IP13928-Ag-1/ GM-Tg-mg-IP13928-Ag-2; GM-Tg-cynog-IP13928-Ag-1/ GM-Tg-cynog-IP13928-Ag-2;
GM-Tg-felg-IP13928-Ag-1/ GM-Tg-felg-IP13928-Ag-2; GM-Tg-cang-IP13928-Ag-1/ GM-Tg-cang-IP13928-Ag-2;
GM-Tg-bovg-IP13928-Ag-1/ GM-Tg-bovg-IP13928-Ag-2; GM-Tg-equg-IP13928-Ag-1/ GM-Tg-equg-IP13928-Ag-2
Products Name IST1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IST1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IST1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.