Recombinant multi-species EIF4A3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF4A3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2400003O03Rik,ATP-dependent RNA helicase DDX48,ATP-dependent RNA helicase eIF4A-3,DDX48,DEAD box protein 48,Ddx48,EIF4A3,Eif4a3,Eukaryotic initiation factor 4A-III,Eukaryotic initiation factor 4A-like NUK-34,Eukaryotic translation initiation factor 4A isoform 3,Fal1,MUK34,NMP265,NUK34,Nuclear matrix protein 265 (NMP 265,RCPS,eIF-4A-III,eIF4A-III,eIF4AIII,hNMP 265),mKIAA0111

Target products collectionGo to EIF4A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13916-Ag-1/ GM-Tg-hg-IP13916-Ag-2 Human EIF4A3 protein Human
GM-Tg-rg-IP13916-Ag-1/ GM-Tg-rg-IP13916-Ag-2 Rat EIF4A3 protein Rat
GM-Tg-mg-IP13916-Ag-1/ GM-Tg-mg-IP13916-Ag-2 Mouse EIF4A3 protein Mouse
GM-Tg-cynog-IP13916-Ag-1/ GM-Tg-cynog-IP13916-Ag-2 Cynomolgus/Rhesus macaque EIF4A3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13916-Ag-1/ GM-Tg-felg-IP13916-Ag-2 Feline EIF4A3 protein Feline
GM-Tg-cang-IP13916-Ag-1/ GM-Tg-cang-IP13916-Ag-2 Canine EIF4A3 protein Canine
GM-Tg-bovg-IP13916-Ag-1/ GM-Tg-bovg-IP13916-Ag-2 Bovine EIF4A3 protein Bovine
GM-Tg-equg-IP13916-Ag-1/ GM-Tg-equg-IP13916-Ag-2 Equine EIF4A3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13916-Ag-1/ GM-Tg-hg-IP13916-Ag-2; GM-Tg-rg-IP13916-Ag-1/ GM-Tg-rg-IP13916-Ag-2;
GM-Tg-mg-IP13916-Ag-1/ GM-Tg-mg-IP13916-Ag-2; GM-Tg-cynog-IP13916-Ag-1/ GM-Tg-cynog-IP13916-Ag-2;
GM-Tg-felg-IP13916-Ag-1/ GM-Tg-felg-IP13916-Ag-2; GM-Tg-cang-IP13916-Ag-1/ GM-Tg-cang-IP13916-Ag-2;
GM-Tg-bovg-IP13916-Ag-1/ GM-Tg-bovg-IP13916-Ag-2; GM-Tg-equg-IP13916-Ag-1/ GM-Tg-equg-IP13916-Ag-2
Products Name EIF4A3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name EIF4A3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF4A3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.