Recombinant multi-species PIGA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PIGA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12. [provided by RefSeq, Jun 2010]
The Alternative Names of target: GPI3,GlcNAc-PI synthesis protein,MCAHS2,NEDEPH,PIG-A,PIGA,PNH1,Phosphatidylinositol N-acetylglucosaminyltransferase subunit A,Phosphatidylinositol-glycan biosynthesis class A protein (PIG-A),Pig-a,Piga

Target products collectionGo to PIGA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1386-Ag-1/ GM-Tg-hg-IP1386-Ag-2 Human PIGA protein Human
GM-Tg-rg-IP1386-Ag-1/ GM-Tg-rg-IP1386-Ag-2 Rat PIGA protein Rat
GM-Tg-mg-IP1386-Ag-1/ GM-Tg-mg-IP1386-Ag-2 Mouse PIGA protein Mouse
GM-Tg-cynog-IP1386-Ag-1/ GM-Tg-cynog-IP1386-Ag-2 Cynomolgus/Rhesus macaque PIGA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1386-Ag-1/ GM-Tg-felg-IP1386-Ag-2 Feline PIGA protein Feline
GM-Tg-cang-IP1386-Ag-1/ GM-Tg-cang-IP1386-Ag-2 Canine PIGA protein Canine
GM-Tg-bovg-IP1386-Ag-1/ GM-Tg-bovg-IP1386-Ag-2 Bovine PIGA protein Bovine
GM-Tg-equg-IP1386-Ag-1/ GM-Tg-equg-IP1386-Ag-2 Equine PIGA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1386-Ag-1/ GM-Tg-hg-IP1386-Ag-2; GM-Tg-rg-IP1386-Ag-1/ GM-Tg-rg-IP1386-Ag-2;
GM-Tg-mg-IP1386-Ag-1/ GM-Tg-mg-IP1386-Ag-2; GM-Tg-cynog-IP1386-Ag-1/ GM-Tg-cynog-IP1386-Ag-2;
GM-Tg-felg-IP1386-Ag-1/ GM-Tg-felg-IP1386-Ag-2; GM-Tg-cang-IP1386-Ag-1/ GM-Tg-cang-IP1386-Ag-2;
GM-Tg-bovg-IP1386-Ag-1/ GM-Tg-bovg-IP1386-Ag-2; GM-Tg-equg-IP1386-Ag-1/ GM-Tg-equg-IP1386-Ag-2
Products Name PIGA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PIGA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PIGA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.