Recombinant multi-species WTAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WTAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. [provided by RefSeq, Jul 2012]
The Alternative Names of target: 2810408K05Rik,9430038B09Rik,Female-lethal(2)D homolog (hFL(2)D),Mum2,Pre-mRNA-splicing regulator WTAP,RGD1563824,WT1-associated protein,WTAP,Wilms tumor 1-associating protein,Wtap

Target products collectionGo to WTAP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13817-Ag-1/ GM-Tg-hg-IP13817-Ag-2 Human WTAP protein Human
GM-Tg-rg-IP13817-Ag-1/ GM-Tg-rg-IP13817-Ag-2 Rat WTAP protein Rat
GM-Tg-mg-IP13817-Ag-1/ GM-Tg-mg-IP13817-Ag-2 Mouse WTAP protein Mouse
GM-Tg-cynog-IP13817-Ag-1/ GM-Tg-cynog-IP13817-Ag-2 Cynomolgus/Rhesus macaque WTAP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13817-Ag-1/ GM-Tg-felg-IP13817-Ag-2 Feline WTAP protein Feline
GM-Tg-cang-IP13817-Ag-1/ GM-Tg-cang-IP13817-Ag-2 Canine WTAP protein Canine
GM-Tg-bovg-IP13817-Ag-1/ GM-Tg-bovg-IP13817-Ag-2 Bovine WTAP protein Bovine
GM-Tg-equg-IP13817-Ag-1/ GM-Tg-equg-IP13817-Ag-2 Equine WTAP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13817-Ag-1/ GM-Tg-hg-IP13817-Ag-2; GM-Tg-rg-IP13817-Ag-1/ GM-Tg-rg-IP13817-Ag-2;
GM-Tg-mg-IP13817-Ag-1/ GM-Tg-mg-IP13817-Ag-2; GM-Tg-cynog-IP13817-Ag-1/ GM-Tg-cynog-IP13817-Ag-2;
GM-Tg-felg-IP13817-Ag-1/ GM-Tg-felg-IP13817-Ag-2; GM-Tg-cang-IP13817-Ag-1/ GM-Tg-cang-IP13817-Ag-2;
GM-Tg-bovg-IP13817-Ag-1/ GM-Tg-bovg-IP13817-Ag-2; GM-Tg-equg-IP13817-Ag-1/ GM-Tg-equg-IP13817-Ag-2
Products Name WTAP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name WTAP
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WTAP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.