Recombinant multi-species PERLD1/PGAP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PERLD1/PGAP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a glycosylphosphatidylinositol (GPI)-specific phospholipase that primarily localizes to the Golgi apparatus. This ubiquitously expressed gene is predicted to encode a seven-transmembrane protein that removes unsaturated fatty acids from the sn-2 position of GPI. The remodeling of the constituent fatty acids on GPI is thought to be important for the proper association between GPI-anchored proteins and lipid rafts. The tethering of proteins to plasma membranes via posttranslational GPI-anchoring is thought to play a role in protein sorting and trafficking. Mutations in this gene cause an autosomal recessive form of neurologic hyperphosphatasia with cognitive disability (HPMRS4). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
The Alternative Names of target: AGLA546,CAB2,COS16 homolog (hCOS16),D430035D22Rik,Gene coamplified with ERBB2 protein,PER1-like domain-containing protein 1,PERLD1,PGAP3,PP1498,Perld1,Pgap3,Post-GPI attachment to proteins factor 3,hCOS16
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1380-Ag-1/ GM-Tg-hg-IP1380-Ag-2 | Human PERLD1/PGAP3 protein | Human |
| GM-Tg-rg-IP1380-Ag-1/ GM-Tg-rg-IP1380-Ag-2 | Rat PERLD1/PGAP3 protein | Rat |
| GM-Tg-mg-IP1380-Ag-1/ GM-Tg-mg-IP1380-Ag-2 | Mouse PERLD1/PGAP3 protein | Mouse |
| GM-Tg-cynog-IP1380-Ag-1/ GM-Tg-cynog-IP1380-Ag-2 | Cynomolgus/Rhesus macaque PERLD1/PGAP3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1380-Ag-1/ GM-Tg-felg-IP1380-Ag-2 | Feline PERLD1/PGAP3 protein | Feline |
| GM-Tg-cang-IP1380-Ag-1/ GM-Tg-cang-IP1380-Ag-2 | Canine PERLD1/PGAP3 protein | Canine |
| GM-Tg-bovg-IP1380-Ag-1/ GM-Tg-bovg-IP1380-Ag-2 | Bovine PERLD1/PGAP3 protein | Bovine |
| GM-Tg-equg-IP1380-Ag-1/ GM-Tg-equg-IP1380-Ag-2 | Equine PERLD1/PGAP3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP1380-Ag-1/ GM-Tg-hg-IP1380-Ag-2;
GM-Tg-rg-IP1380-Ag-1/ GM-Tg-rg-IP1380-Ag-2;
GM-Tg-mg-IP1380-Ag-1/ GM-Tg-mg-IP1380-Ag-2; GM-Tg-cynog-IP1380-Ag-1/ GM-Tg-cynog-IP1380-Ag-2; GM-Tg-felg-IP1380-Ag-1/ GM-Tg-felg-IP1380-Ag-2; GM-Tg-cang-IP1380-Ag-1/ GM-Tg-cang-IP1380-Ag-2; GM-Tg-bovg-IP1380-Ag-1/ GM-Tg-bovg-IP1380-Ag-2; GM-Tg-equg-IP1380-Ag-1/ GM-Tg-equg-IP1380-Ag-2 |
| Products Name | PERLD1/PGAP3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PERLD1/PGAP3 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PERLD1/PGAP3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.