Recombinant multi-species PGAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene functions early in the glycosylphosphatidylinositol (GPI) biosynthetic pathway, catalyzing the inositol deacylation of GPI. The encoded protein is required for the production of GPI that can attach to proteins, and this may be an important factor in the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi. Defects in this gene are a cause an autosomal recessive form of cognitive impairment. [provided by RefSeq, Jul 2017]
The Alternative Names of target: 5033403E17Rik,9030223K07Rik,A530084K22,Bst1,D230012E17Rik,GPI inositol-deacylase,ISPD3024,MRT42,NEDDSBA,PGAP1,Pgap1,Post-GPI attachment to proteins factor 1 (hPGAP1),SPG67,oto
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1378-Ag-1/ GM-Tg-hg-IP1378-Ag-2 | Human PGAP1 protein | Human |
| GM-Tg-rg-IP1378-Ag-1/ GM-Tg-rg-IP1378-Ag-2 | Rat PGAP1 protein | Rat |
| GM-Tg-mg-IP1378-Ag-1/ GM-Tg-mg-IP1378-Ag-2 | Mouse PGAP1 protein | Mouse |
| GM-Tg-cynog-IP1378-Ag-1/ GM-Tg-cynog-IP1378-Ag-2 | Cynomolgus/Rhesus macaque PGAP1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1378-Ag-1/ GM-Tg-felg-IP1378-Ag-2 | Feline PGAP1 protein | Feline |
| GM-Tg-cang-IP1378-Ag-1/ GM-Tg-cang-IP1378-Ag-2 | Canine PGAP1 protein | Canine |
| GM-Tg-bovg-IP1378-Ag-1/ GM-Tg-bovg-IP1378-Ag-2 | Bovine PGAP1 protein | Bovine |
| GM-Tg-equg-IP1378-Ag-1/ GM-Tg-equg-IP1378-Ag-2 | Equine PGAP1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP1378-Ag-1/ GM-Tg-hg-IP1378-Ag-2;
GM-Tg-rg-IP1378-Ag-1/ GM-Tg-rg-IP1378-Ag-2;
GM-Tg-mg-IP1378-Ag-1/ GM-Tg-mg-IP1378-Ag-2; GM-Tg-cynog-IP1378-Ag-1/ GM-Tg-cynog-IP1378-Ag-2; GM-Tg-felg-IP1378-Ag-1/ GM-Tg-felg-IP1378-Ag-2; GM-Tg-cang-IP1378-Ag-1/ GM-Tg-cang-IP1378-Ag-2; GM-Tg-bovg-IP1378-Ag-1/ GM-Tg-bovg-IP1378-Ag-2; GM-Tg-equg-IP1378-Ag-1/ GM-Tg-equg-IP1378-Ag-2 |
| Products Name | PGAP1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PGAP1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGAP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.