Recombinant multi-species HAND2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HAND2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Class A basic helix-loop-helix protein 26 (bHLHa26),DHAND,DHAND2,Deciduum,Ehand2,HAND2,Hand2,Heart- and neural crest derivatives-expressed protein 2,Hed,Th2,Thing2,autonomic nervous system and neural crest derivatives-expressed protein 2 (dHAND),bHLHa26,dHAND,dHand,heart

Target products collectionGo to HAND2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13769-Ag-1/ GM-Tg-hg-IP13769-Ag-2 Human HAND2 protein Human
GM-Tg-rg-IP13769-Ag-1/ GM-Tg-rg-IP13769-Ag-2 Rat HAND2 protein Rat
GM-Tg-mg-IP13769-Ag-1/ GM-Tg-mg-IP13769-Ag-2 Mouse HAND2 protein Mouse
GM-Tg-cynog-IP13769-Ag-1/ GM-Tg-cynog-IP13769-Ag-2 Cynomolgus/Rhesus macaque HAND2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13769-Ag-1/ GM-Tg-felg-IP13769-Ag-2 Feline HAND2 protein Feline
GM-Tg-cang-IP13769-Ag-1/ GM-Tg-cang-IP13769-Ag-2 Canine HAND2 protein Canine
GM-Tg-bovg-IP13769-Ag-1/ GM-Tg-bovg-IP13769-Ag-2 Bovine HAND2 protein Bovine
GM-Tg-equg-IP13769-Ag-1/ GM-Tg-equg-IP13769-Ag-2 Equine HAND2 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13769-Ag-1/ GM-Tg-hg-IP13769-Ag-2; GM-Tg-rg-IP13769-Ag-1/ GM-Tg-rg-IP13769-Ag-2;
GM-Tg-mg-IP13769-Ag-1/ GM-Tg-mg-IP13769-Ag-2; GM-Tg-cynog-IP13769-Ag-1/ GM-Tg-cynog-IP13769-Ag-2;
GM-Tg-felg-IP13769-Ag-1/ GM-Tg-felg-IP13769-Ag-2; GM-Tg-cang-IP13769-Ag-1/ GM-Tg-cang-IP13769-Ag-2;
GM-Tg-bovg-IP13769-Ag-1/ GM-Tg-bovg-IP13769-Ag-2; GM-Tg-equg-IP13769-Ag-1/ GM-Tg-equg-IP13769-Ag-2
Products Name HAND2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HAND2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HAND2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.