Recombinant multi-species DDX21 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DDX21 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
The Alternative Names of target: D10Ertd645e,D10Wsu42e,DDX21,DEAD box protein 21,Ddx21,Ddx21a,Ddx21b,GUA,GURDB,Gu-alpha,II/Gu,Nucleolar RNA helicase 2,Nucleolar RNA helicase Gu,Nucleolar RNA helicase II,RH,RH II/Gu,RH-II/GU,RH-II/GuA,gu-alpha
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP13572-Ag-1/ GM-Tg-hg-IP13572-Ag-2 | Human DDX21 protein | Human |
| GM-Tg-rg-IP13572-Ag-1/ GM-Tg-rg-IP13572-Ag-2 | Rat DDX21 protein | Rat |
| GM-Tg-mg-IP13572-Ag-1/ GM-Tg-mg-IP13572-Ag-2 | Mouse DDX21 protein | Mouse |
| GM-Tg-cynog-IP13572-Ag-1/ GM-Tg-cynog-IP13572-Ag-2 | Cynomolgus/Rhesus macaque DDX21 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP13572-Ag-1/ GM-Tg-felg-IP13572-Ag-2 | Feline DDX21 protein | Feline |
| GM-Tg-cang-IP13572-Ag-1/ GM-Tg-cang-IP13572-Ag-2 | Canine DDX21 protein | Canine |
| GM-Tg-bovg-IP13572-Ag-1/ GM-Tg-bovg-IP13572-Ag-2 | Bovine DDX21 protein | Bovine |
| GM-Tg-equg-IP13572-Ag-1/ GM-Tg-equg-IP13572-Ag-2 | Equine DDX21 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP13572-Ag-1/ GM-Tg-hg-IP13572-Ag-2;
GM-Tg-rg-IP13572-Ag-1/ GM-Tg-rg-IP13572-Ag-2;
GM-Tg-mg-IP13572-Ag-1/ GM-Tg-mg-IP13572-Ag-2; GM-Tg-cynog-IP13572-Ag-1/ GM-Tg-cynog-IP13572-Ag-2; GM-Tg-felg-IP13572-Ag-1/ GM-Tg-felg-IP13572-Ag-2; GM-Tg-cang-IP13572-Ag-1/ GM-Tg-cang-IP13572-Ag-2; GM-Tg-bovg-IP13572-Ag-1/ GM-Tg-bovg-IP13572-Ag-2; GM-Tg-equg-IP13572-Ag-1/ GM-Tg-equg-IP13572-Ag-2 |
| Products Name | DDX21 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DDX21 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DDX21 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.